矽肺和石棉肺中的血管紧张素转换酶和溶菌酶。

C Grönhagen-Riska, K Kurppa, F Fyhrquist, O Selroos
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引用次数: 0

摘要

对22例矽肺和18例石棉肺患者血清血管紧张素转换酶(ACE)活性和溶菌酶(LZM)浓度进行了研究。这些患者与57例未治疗和36例治疗的结节病患者进行比较。各组ACE和LZM均值均显著升高。未经治疗的结节病患者值最高。在矽肺和石棉肺中,ACE活性升高以前未见报道,这削弱了这种酶测定对结节病的鉴别诊断价值。在所有三种疾病中,ACE和LZM平均值的增加模式相似,表明这些酶有一个共同的来源。
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Angiotensin-converting enzyme and lysozyme in silicosis and asbestosis.

Serum angiotensin-converting enzyme (ACE) activity and lysozyme (LZM) concentration in 22 silicosis and 18 asbestosis patients were studied. These patients were compared with 57 untreated and 36 treated sarcoidosis patients. In all groups significantly raised ACE and LZM mean values were noted. Untreated sarcoidosis patients had the highest values. Raised ACE activity in silicosis and asbestosis has not been reported before, and weakens the differential diagnostic value of this enzyme determination for sarcoidosis. The similar patterns of increased ACE and LZM mean values in all three diseases suggest that these enzymes have a common source.

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Circulating immune complexes, free antigen and alpha 1-antitrypsin in levels in sarcoidosis patients. Pulmonary damage associated with gold therapy. A report of two cases. Angiotensin converting enzyme. III. Changes in serum level as an indicator of disease activity in untreated sarcoidosis. Angiotensin converting enzyme. IV. Changes in serum activity and in lysozyme concentrations as indicators of the course of untreated sarcoidosis. Influence of age on bronchial mucociliary transport.
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