类固醇性高血压大鼠动脉钠钾泵活性的改变。

Clinical science and molecular medicine. Supplement Pub Date : 1978-12-01 DOI:10.1042/cs055041s

M B Pamnani, D L Clough, F J Haddy

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引用次数: 72

摘要

1. 用脱氧皮质酮和生理盐水治疗高血压大鼠尾动脉，研究了瓦巴因对86Rb的敏感摄取(Na+-K+泵活性的量度)。2. 瓦巴因敏感钠钾泵活性的降低支持了钠钾泵活性在体积扩张型高血压中受到抑制的假设。

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Altered activity of the sodium-potassium pump in arteries of rats with steroid hypertension.

1. Ouabain-sensitive uptake of 86Rb, a measure of the Na+-K+ pump activity, was studied in tail arteries of rats made hypertensive with deoxycorticosterone and saline. 2. Decreased activity of the ouabain-sensitive Na+-K+ pump supports the hypothesis that the activity of Na+-K+ pump is suppressed in volume expanded hypertension.

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Clinical science and molecular medicine. Supplement

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