大鼠内皮和间皮缺乏Fc受体

D. Geiling, H.G. Geiling, K.J. Halbhuber, R. Fröber, G. Geyer
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引用次数: 3

摘要

本研究研究了在不同预处理和孵育条件下,大鼠内皮和间皮与同种红细胞的相互作用。研究结果表明,大鼠内皮细胞和间皮细胞(1)无论培养基中是否存在γ -球蛋白,对天然或预处理的红细胞都不具有粘附性;(2)缺乏对IgG分子Fc段敏感的初级或隐性受体;(3)在氧化糖萼上具有结合位点,与修饰红细胞的受体群共享同一类IgG。
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Rat endo- and mesothelium lack Fc receptors

The present study is concerned with the interaction of rat endo- and mesothelium with homologous erythrocytes under various conditions of pretreatment and incubation. Its findings show rat endo- and mesothelial cells

  • a)

    nonadhesive to native or pretreated erythrocytes irrespective of the presence of gamma-globulin in the medium,

  • b)

    devoid of primary or cryptic receptors sensitive to the Fc segment of the IgG molecule, and

  • c)

    provided with binding sites at the oxidized glycocalyx which together with receptor groups of modified erythrocytes share the same class of IgG.

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