Postoperative Analgesia In Laparoscopic Cholecystectomy: A Comparative Study Using Bupivacaine Instillation And Infiltration Versus Parenteral Analgesia (Tramadol).

In a prospective randomized double blind clinical study, 120 patients of either sex in the age group of 25-65 years with ASA I and II, who were scheduled to undergo elective laparoscopic cholecystectomy were allocated to two groups of 60 patients each with regard to postoperative analgesia. In Group-I (n=60) the patients received Bupivacaine (0.5%) 20ml, instilled in gallbladder bed and the undersurface of diaphragm and infiltration of port wounds. In Group-II (n=60) the patients were provided with postoperative analgesia with Tramadol (100mg) given intramuscularly (IM) at the completion of procedure. The postoperative analgesia was assessed using Visual Analogue Scale (VAS) at hourly intervals for first four hours and then 24 hours also. Vital signs like Spo2, HR, NIBP, RR were recorded six hourly for 24 hours postoperatively. There was statistically significant (p value<0.05) better analgesia in Group-II (Tramadol group) as compared to Group-I (Bupivacaine group).