特定COVID-19大流行地区静脉和动脉血栓栓塞高发生率高并发症:是否存在携带遗传易感性的人群聚集性评估?

G. Lazzar, V. Speciale, G. Silvano
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引用次数: 0

摘要

COVID-19肺炎中的凝血功能障碍是一种有害的并发症,已导致全球多个人群的高死亡率,如2020年3月大流行期间意大利北部红区的死亡率。由于血栓栓塞(TE)事件在几个相关人群中的高发,由于参与凝血过程的几个基因的多态性,可能会形成和研究一种遗传易感性。
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High incidence of venous and arterial thrombo embolic high complications in specific COVID-19 pandemic areas: are there clusters of populations carrying an hereditary predisposition to assess?
Coagulopathy in COVID-19 pneumonia is a deleteroius complication which has lead to a high rate of deaths in several populations world wide like in Northern Italy Red Zone during pandemic time in March 2020. Due to an high incidence of thrombo embolic (TE) events among several clusters of involved populations, a suspect of an hereditary predisposition due to polymorphisms in several genes involved in the caoagulation process could be formulated and investigated.
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