血清低密度脂蛋白水平预测非体外循环冠状动脉搭桥手术后糖尿病患者的中期预后

Tomoaki Izawa, K. Kajimoto, Taira Yamamoto, K. Miyauchi, H. Inaba, K. Tambara, S. Dohi, T. Iwamura, Yuki Yoneda, R. Tsuruta, H. Daida, A. Amano
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引用次数: 0

摘要

在冠状动脉疾病的二级预防中,低密度脂蛋白胆固醇(LDL─C)水平升高和糖尿病等疾病与不良事件风险增加有关。这些代谢紊乱也与冠状动脉搭桥手术后的不良事件有关。然而,很少有报道描述了术后结果与术前血清中介物水平的关系,包括空腹血糖(FBS)、血红蛋白A1c(HbA1c)和LDL─C水平。本研究评估了代谢产物(包括LDL─C)对非体外循环冠状动脉搭桥手术后糖尿病患者中期预后的影响。患者:我们招募了350名糖尿病患者,他们在2003年至2007年间在我们的机构接受了孤立的非体外循环冠状动脉搭桥手术。:全因死亡、心源性死亡和心脑血管事件(MACCE)的预测因子,经LDL─C、FBS和其他危险因素校正后的Cox比例危险度
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Serum Low-Density Lipoprotein Levels Predict Mid-Term Outcomes of Diabetic Patients After Off-Pump Coronary Artery Bypass Surgery
disorders, such as higher low-density lipoprotein cholesterol(LDL─C) levels and diabetes mellitus are associated with an increased risk of adverse events in the secondary prevention of coronary artery disease. These metabolic disorders are also associated with adverse events after coronary artery bypass surgery. However, few reports describe the relationship between postoperative outcomes and preoperative serum levels of mediators including levels of fasting blood sugar (FBS), hemoglobin A1c(HbA1c) and LDL─C. This study assesses the impact of metabolic makers, including LDL─C, on mid-term outcomes of patients with diabetes after off-pump coronary artery bypass surgery. Patients :We enrolled 350 diabetic patients who underwent isolated off-pump coronary artery bypass surgery at our institu-tion between 2003 and 2007. :Predictors of all-cause death, cardiac death, and cardiac and cerebrovascular events(MACCE) the Cox proportional-hazards adjusted for LDL─C, FBS and other risk factors at
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