Bioengineered Immunotherapy Techniques for the Treatment of Select Secondary Immunodeficiency Disorders

The inner workings of the immune system are quite complex. Each component works diligently in order to protect us from invaders such as pathogens: viruses, microbes, and fungi. Unfortunately, the immune system may become dysfunctional, which can result in secondary immunodeficiency diseases. The treatments available for these disorders and diseases of the immune system do not typically serve to cure, and much too often the side effects associated can exacerbate the conditions. As an alternative, the area of immunotherapy seeks to remedy the limitations of today’s medicine. Through this review, insight into the current conventional treatments available for select secondary immunodeficiency diseases will be provided, particularly in Human Immunodeficiency Virus disease and Systemic Lupus Erythematosus. The modern immunotherapy approaches that are underway will then be analyzed in their capacity and potential to treat these defects of the immune system. 2-block-ing antibody. With the use of a humanized Bone marrow-liver-thymus (BLT) mouse, it was found that there was decreased immune activation, decreased expression of T cell exhaustion markers and reduced plasma viral loads. IFN-I induces antitumor responses, promotes CD8 + T cell priming. Using this thera- py in conjunction with ART result- ed in rapid viral suppression. Also reduced viral reservoirs. [14]