用于药物开发和生物医学研究的个人食品计算机自动化

Almog Boanos, S. Chandrababu, D. Bastola
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引用次数: 0

摘要

植物次生代谢物是帮助植物适应环境的关键因子,也是药物的重要来源。如今,使用生长环境室只是为了提高工厂的整体产量,而对其质量关注较少。自动化策略可以应用于调整现有模型,使其兼容于精确控制环境因素,这些因素是次生代谢物代谢途径变化的重要影响因素。此前,麻省理工学院开发了一种个人食品计算机(PFC)来控制植物的生长环境,以保持城市环境中植物生产的均匀性。然而,仍有一些挑战未被触及,特别是当PFC用于研究设置时。其中一个例子是日光的增加对湿度水平产生了负面影响,这可能是不希望的,需要人工干预来保持生长条件的稳定性。为了克服现有模型的缺点,我们通过实施基于云的灵活自动化技术以及机器人技术来修改麻省理工学院的PFC,以开发具有成本效益的自动化食品计算机(CEAFC)。本文旨在解决CEAFC的自动化特征及其在生产具有治疗价值的次级代谢物中的雄辩用途。
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Automation of Personal Food Computers for Research in Drug Development and Biomedicine
Plant secondary metabolites are critical factors that aid plants in adaptation to their environment and are important sources of pharmaceuticals. Growth environment chambers nowadays are employed only to improve the overall production of the plant, while paying less attention to its quality. Automated strategies can be applied to attune the existing model, making it compatible for precisely controlling the environmental factors, which are the significant effectors of changes in the metabolic pathways of secondary metabolites. Previously, MIT has developed a Personal Food Computer (PFC) to control the growth environment of plants to maintain uniformity in their production in an urban setting. However, several challenges remained untouched, especially when the PFC was used in a research setting. One such instance was that an increase in the daylight negatively impacted the level of humidity, which could be undesirable and requires manual intervention to maintain grow-condition stability. To overcome the shortcomings of the existing model we have modified MIT's PFC by implementing cloud-based flexible automation techniques along with robotics to develop a Cost-Effective Automated Food Computer (CEAFC). The present article is aimed at addressing the automated features of CEAFC and its eloquent use in the production of secondary metabolites of therapeutic value.
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