水烟(水管)吸烟对卡诺市吸烟者血脂和抗氧化维生素的影响

I. M., Waziri B I, A. A, Atiku M K
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摘要

水烟是冠心病的危险因素之一。烟雾中含有大量的化学物质,这些化学物质能够产生活性氧,而活性氧在氧化应激中起着重要作用,从而导致许多疾病的发生和发展,如高血压、癌症、糖尿病和心血管疾病。监测血脂(高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和甘油三酯)和抗氧化维生素(A、C和E)水平对于了解水烟吸烟对血脂和抗氧化维生素的影响非常重要。本研究旨在探讨卡诺市50例明显健康的水烟吸烟者(暴露组)吸水烟对血脂及抗氧化维生素的影响。相应的50名(50)明显健康的非吸烟者作为对照(非暴露组)。与对照组相比,水烟吸烟与吸烟者总胆固醇(TC)、甘油三酯、低密度脂蛋白胆固醇水平升高显著相关(p小于0.05)。但与未暴露组相比,暴露组hdl -胆固醇和血清抗氧化维生素(a、C、E)显著(p>0.05)降低。本研究结果还表明,长期暴露于水烟后,人体脂质和抗氧化维生素含量略有增加,但两者之间的关系无统计学意义(p>0.05)。研究结果表明,水烟会导致血脂异常和氧化应激。
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Effect of Shisha (Water-Pipe) Smoking on Serum Lipid Profile and Antioxidant Vitamins among Smokers in Kano Metropolis
Shisha Smoking is a risk factor for coronary heart diseases. The smoke contains large amount of chemicals which are capable of generating reactive oxygen species which play an important role in oxidative stress which in turn leads to the development and progression of many disorders such as hypertension, cancer, diabetes mellitus and cardiovascular diseases. Monitoring lipid profile (HDL-cholesterol, LDL-cholesterol and triacylgycerides) and antioxidant vitamins (A, C and E) levels is very important to give an insight on the effect of shisha smoking on lipid profile and antioxidant vitamins. This study aimed to determine the effect of shisha smoking on serum lipid profile, and antioxidant vitamins in fifty (50) apparently healthy shisha smokers (exposed group) in Kano metropolis. A corresponding fifty (50) apparently healthy non-smokers were used as controls (non exposed group). The Shisha smoking was significantly associated with increased levels of total cholesterol (TC), triglyceride, LDL-cholesterol (p˂0.05) in smokers compared to control group. However, there was a significant (p>0.05) decrease in HDL-cholesterol and serum antioxidant vitamins (A, C and E) in exposed group compared to non-exposed group. The results of this study also indicate that exposure of human being to shisha smoke over a period of time causes slight increase in lipid profile and antioxidant vitamins but the relation was statistically not significant (p>0.05). The findings suggest that shisha smoking causes dyslipidaemia and oxidative stress.
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