免疫功能正常的宿主中分离的肺禽分枝杆菌复合体感染1例

Sivanthi Rajendran, Gayathri Ramakrishnan
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引用次数: 0

摘要

男性,48岁,过去4个月偶有干咳和打喷嚏,胸部高分辨率计算机断层扫描显示树状芽状影,右上肺叶和右中肺叶斑片状结节性混浊。他接受了支气管镜检查和支气管肺泡灌洗,未检出基因X-pert结核分枝杆菌(MTB),但细胞学检查显示肉芽肿,因此他开始接受经验性抗结核治疗(异烟肼、利福平、吡嗪酰胺和乙胺丁醇(HRZE)方案)。随访期间抗酸杆菌C/S报告显示禽分枝杆菌复合体(MAC)生长。进行了药物敏感性测试,然后开始口服利福平、乙胺丁醇和阿奇霉素,并在接下来的6个月里继续使用这种治疗方案。
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A case of isolated pulmonary Mycobacterium avium complex infection in an immunocompetent host
A 48-year-old male presented with complaints of occasional dry cough and sneezing for the past 4 months and high-resolution computed tomography chest done showed tree in bud and patchy nodular opacities in the right upper lobe and right middle lobe. He underwent bronchoscopy and bronchoalveolar lavage Gene X-pert Mycobacterium Tuberculosis (MTB) was not detected, but cytology showed granulomas and hence he was started on empirical antituberculous therapy (Isoniazid, Rifampicin, Pyrazinamide and Ethambutol (HRZE) regimen). His acid-fast bacilli C/S reports during follow-up showed growth of Mycobacterium Avium complex (MAC). Drug sensitivity testing was done and then he was started on oral rifampicin, ethambutol, and azithromycin and this regimen was continued for the next 6 months.
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