In Vitro gardicidal and amoebicidal activity of Anogeissus leicarpus leaves extracts

The infection of intestinal parasite is one of the most familiar in the outgrowth countries its negatively effects on the feed and healthy case of human.1 Some of the intestinal parasites cause sudden and acute diarrhea continues for many days as in cases of giardiasis and amoebiasis.2 The intestinal parasites may be caused anemia and a different grade of malnutrition.3 Giardia lamblia and Entamoeba histolytica are microaerophilic protists, which cause dysentery and diarrhea, respectively.4,5 Each is a single cell protist with a motile trophozoite stage and an immotile cyst stage. In many other ways amoebae and giardia are quite dissimilar. Amoebae have a single diploid nucleus, while giardia has two similar nuclei. While amoebae move along surfaces by an actinimyosin-mediated crawl, giardia swim by the synchronous beating of flagella and adhere to surfaces by means of a unique ventral disc.6 Giardiasis is one of the intestinal protozoa that cause public health problems in most developing countries as well as some developed countries. Gisardia lamblia is considered to be one of the leading causative agents of diarrhea in both children and adults.7–11 Giardiasis is the most common cause of parasitic gastro-intestinal disease and it is estimated that up to two hundred million people are chronically infected with Giardia lamblia globally, and 500,000 new cases reported annually.12 The prevalence of the disease varies from 2% 5% in developed to 20% 30% in developing countries. The variation in prevalence depends on factors such as the geographical area, the urban or rural setting of the society, the age group composition and the socio-economic conditions of the study subject,13 mortality world-wide.14