阿片类药物简介

Adekunle Ademikanra, Azeemat Olayiwola, Olutayo Oyewole
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引用次数: 0

摘要

阿片类药物是一种精神活性化学物质,可以减轻疼痛感。它们是一类药物,与抑制中枢神经系统有关,并引起几种生理和心理反应,包括麻木、诱导睡眠、多动、嗜睡、精神错乱、恶心、兴奋以及便秘。最常见的阿片类药物有曲马多、海洛因、吗啡、可待因等。阿片类药物使用的主要原因是为了治疗目的。然而,阿片类药物的使用也被广泛地与增加能量和性欲有关。它也被用作对抗压力、创伤后压力、贫穷、犯罪等影响的应对机制。滥用阿片类药物通常与过量、成瘾和戒断有关。本研究的重点是尼日利亚阿片类药物使用的发生率,这已成为该国所有地区的流行病。可待因和曲马多是尼日利亚主要类型的阿片类药物,除了是止咳糖浆的有效成分外,据报道,它们是尼日利亚人健康问题和死亡的主要原因,不分宗教、性别、年龄、社会和教育背景。由于可待因和曲马多的可获得性、易获得性、相对可负担性以及它们引起的欣快感,可待因和曲马多被大量滥用。有记录的阿片类药物过量致死事件和阿片类药物与印度大麻等其他药物之间的不良相互作用。阿片类药物的成瘾能力和由此产生的反社会行为、致死率和潜在的健康影响使阿片类药物的使用成为社会的威胁。因此,这一威胁促使政府采取措施,强制减少阿片类药物的使用。
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Introduction to Opioids
Opioids are psychoactive chemical substances that have been known to reduce feelings of pain. They are a class of drugs that have been implicated in depressing the central nervous system and causing several physical and psychological reactions including numbness, inducing sleep, hyperactivity, drowsiness, mental confusion, nausea, euphoria as well as constipation. The commonest examples of opioids are tramadol, heroin, morphine, codeine, etc. The main reason for Opioid use is for therapeutic purposes. However, the use of Opioids has also been widely implicated in increasing energy and libido. It is also used as a coping mechanism against pressure, the impact of post-traumatic stress, poverty, crime, etc. The indiscriminate use of opioids is usually associated with overdose, addiction and withdrawal.  This study focuses on the incidence of opioid use in Nigeria that has become an epidemic in all regions of the country. In addition to being an active component of cough syrups, Codeine and tramadol which are the predominant types of opioids in Nigeria, have been reported to be a leading cause of health implications and fatality amongst Nigerians, cutting across religion, gender, age, social and educational backgrounds. Due to their availability, ease of accessibility, relative affordability, and the euphoric sensation they cause, Codeine and Tramadol have been tremendously used indiscriminately. There are recorded incidents of fatal overdose and adverse interactions between opioids and other drug classes such as Indian hemp. The addictive ability and the resultant antisocial behaviour, fatality and potential health implication poses Opioid use as a threat in the society. This menace has therefore incited the government to put measures in place to enforce the reduction in Opioid use.
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