С.В. Зубков, Олена Петрикей, Інна Богайчук-Козій
{"title":"МОДЕЛЮВАННЯ БІОЛОГІЧНИХ ОБ’ЄКТІВ ПРИ РОЗРОБЦІ ПРИСТРОЮ ДЛЯ ТРАНСКРАНІАЛЬНОЇ СТИМУЛЯЦІЇ ПОСТІЙНИМ СТРУМОМ","authors":"С.В. Зубков, Олена Петрикей, Інна Богайчук-Козій","doi":"10.20535/2617-8974.2019.2.185339","DOIUrl":null,"url":null,"abstract":"In medical practice, electrotherapy procedures based on the effects of currents of different frequencies are used for treatment and prophylaxis. Their mechanisms of action and characteristics of incentives in different biological structures are studied insufficiently. The actuality of work is due to thepresence of a wide range of pathological and limiting states that are subjected to treatment through physiotherapeutic effects on various parts of the nervous system, which is confirmed by studies of leading universities of the world and a significant interest of users of typical devices for: rapid recovery of physical condition (replacement of pharmacological agents); stimulation of physical abilities of an organism (training of athletes); stimulation of mental abilities (preparation for examinations); treatment of speech impairment in the sensitivity of psychological and emotional state. An analysis of the paths of current propagation with non-invasive effects requires the consideration of possible biophysical mechanisms of the effect of weak current on the brain through the ankle electrodes. The amount of energy supplied to the patient and the depth of the signal penetration is a factor in the effectiveness of stimulation, because due to the correct choice of these parameters, the period of treatment decreases and the effectiveness of the procedure increases. The basic principle of neurostimulation is to obtain an optimal physiological effect under the condition of minimal side effects, which determines the use of different currents, depending on the tissue excitability and their functional state. The physical bases of transcranial stimulation by direct current areanalyzed in the article. The equivalent electrical scheme of the model of the investigated object is substantiated. The behavior of biological structures is described by an equivalent electric circuit, the resistors and capacitors of which correspond to the resistance and capacitance of the membrane and the intercellular fluid. The construction and modeling was carried out in Micro-Cap 9.As a result of a computer experiment, it became clear that a cell conglomerate can be replaced by one equivalent cell: the nature of the impedance curve does not change, and only its spreading varies","PeriodicalId":386518,"journal":{"name":"Біомедична інженерія і технологія","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2018-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Біомедична інженерія і технологія","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20535/2617-8974.2019.2.185339","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

在医疗实践中,基于不同频率电流效果的电疗程序用于治疗和预防。它们在不同生物结构中的作用机制和激励特征研究不够。工作的现状是由于广泛的病理和限制状态的存在,这些状态通过物理治疗作用于神经系统的各个部分进行治疗,世界一流大学的研究证实了这一点,并且典型设备的用户非常感兴趣:快速恢复身体状况(替代药物);训练:刺激机体的体能(运动员的训练);刺激智力(准备考试);治疗言语障碍中的敏感心理和情绪状态。对具有非侵入性效应的电流传播路径的分析需要考虑弱电通过踝关节电极对大脑产生影响的可能生物物理机制。提供给患者的能量和信号穿透的深度是刺激有效性的一个因素,因为由于这些参数的正确选择,治疗周期缩短,程序的有效性增加。神经刺激的基本原理是在副作用最小的条件下获得最佳的生理效果,这就决定了根据组织的兴奋性及其功能状态,使用不同的电流。本文分析了经颅直流电刺激的物理基础。证实了所研究对象模型的等效电方案。生物结构的行为用等效电路来描述,其中的电阻和电容对应于膜和细胞间液的电阻和电容。在Micro-Cap 9中进行了构建和建模。计算机实验的结果表明,一个细胞群可以被一个等效的细胞所取代:阻抗曲线的性质不会改变,只有它的扩散会改变
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
МОДЕЛЮВАННЯ БІОЛОГІЧНИХ ОБ’ЄКТІВ ПРИ РОЗРОБЦІ ПРИСТРОЮ ДЛЯ ТРАНСКРАНІАЛЬНОЇ СТИМУЛЯЦІЇ ПОСТІЙНИМ СТРУМОМ
In medical practice, electrotherapy procedures based on the effects of currents of different frequencies are used for treatment and prophylaxis. Their mechanisms of action and characteristics of incentives in different biological structures are studied insufficiently. The actuality of work is due to thepresence of a wide range of pathological and limiting states that are subjected to treatment through physiotherapeutic effects on various parts of the nervous system, which is confirmed by studies of leading universities of the world and a significant interest of users of typical devices for: rapid recovery of physical condition (replacement of pharmacological agents); stimulation of physical abilities of an organism (training of athletes); stimulation of mental abilities (preparation for examinations); treatment of speech impairment in the sensitivity of psychological and emotional state. An analysis of the paths of current propagation with non-invasive effects requires the consideration of possible biophysical mechanisms of the effect of weak current on the brain through the ankle electrodes. The amount of energy supplied to the patient and the depth of the signal penetration is a factor in the effectiveness of stimulation, because due to the correct choice of these parameters, the period of treatment decreases and the effectiveness of the procedure increases. The basic principle of neurostimulation is to obtain an optimal physiological effect under the condition of minimal side effects, which determines the use of different currents, depending on the tissue excitability and their functional state. The physical bases of transcranial stimulation by direct current areanalyzed in the article. The equivalent electrical scheme of the model of the investigated object is substantiated. The behavior of biological structures is described by an equivalent electric circuit, the resistors and capacitors of which correspond to the resistance and capacitance of the membrane and the intercellular fluid. The construction and modeling was carried out in Micro-Cap 9.As a result of a computer experiment, it became clear that a cell conglomerate can be replaced by one equivalent cell: the nature of the impedance curve does not change, and only its spreading varies
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
СИСТЕМА ДЛЯ ВИЗНАЧЕННЯ ОСОБЛИВОСТЕЙ ХОДИ У ПАЦІЄНТІВ З ТРАНСТИБІАЛЬНОЮ АМПУТАЦІЄЮ ДОСЛІДЖЕННЯ АЛЬТЕРНАТИВНОГО КОМПОЗИТНОГО МАТЕРІАЛУ В КОНСТРУКЦІЇ ЗОВНІШНІХ ПРОТЕЗІВ НИЖНІХ КІНЦІВОК ЛЮДИНИ УДОСКОНАЛЕННЯ КОМП’ЮТЕРНОЇ МОДЕЛІ ДЛЯ ОБРОБКИ ТА АНАЛІЗУ СПЕКЛ-ІНТЕРФЕРОГРАМ КРОВІ ЛЮДИНИ ПРОГРАМНО-АПАРАТНИЙ КОМПЛЕКС ДЛЯ ОНЛАЙН-ВЗАЄМОДІЇ ЛІКАРЯ І ПАЦІЄНТА З COVID-19 ЗМЕНШЕННЯ ВТРАТ ЛІКІВ ПРИ НЕБУЛАЙЗЕРНІЙ ТЕРАПІЇ
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1