{"title":"生物玻璃在慢性局灶性骨髓炎治疗中的作用。","authors":"ORTEGA YAGO, ARGÜELLES LINARES, BAEZA OLIETE","doi":"10.37315/sotocav20222905740","DOIUrl":null,"url":null,"abstract":"Bioactive glass emerges as an alternative to the classic two-stage treatment of chronic focal osteomyelitis. It allows the eradication of the infection in a single surgical act without the need to add a local antibiotic thanks to its mechanism of action, facilitating the filling of the residual bone defect after debridement. A retrospective review of 29 patients treated with bioactive glass was carried out in order to analyze the results and secondary complications. We observed a significant improvement in the analytical parameters, with complete remission of the infection in 80% of the patients. 31% showed wound serum leakage with spontaneous resolution in 55% of patients in the first 7 days after surgery. Therefore, bioactive glass is effective against multiple microorganisms, with good results in recurrence rate and few complications, even though long-term studies are required to confirm these results.","PeriodicalId":202353,"journal":{"name":"Revista Española de Cirugía Osteoarticular","volume":"89 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Papel del biovidrio en el tratamiento de la osteomielitis focal crónica.\",\"authors\":\"ORTEGA YAGO, ARGÜELLES LINARES, BAEZA OLIETE\",\"doi\":\"10.37315/sotocav20222905740\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Bioactive glass emerges as an alternative to the classic two-stage treatment of chronic focal osteomyelitis. It allows the eradication of the infection in a single surgical act without the need to add a local antibiotic thanks to its mechanism of action, facilitating the filling of the residual bone defect after debridement. A retrospective review of 29 patients treated with bioactive glass was carried out in order to analyze the results and secondary complications. We observed a significant improvement in the analytical parameters, with complete remission of the infection in 80% of the patients. 31% showed wound serum leakage with spontaneous resolution in 55% of patients in the first 7 days after surgery. Therefore, bioactive glass is effective against multiple microorganisms, with good results in recurrence rate and few complications, even though long-term studies are required to confirm these results.\",\"PeriodicalId\":202353,\"journal\":{\"name\":\"Revista Española de Cirugía Osteoarticular\",\"volume\":\"89 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Española de Cirugía Osteoarticular\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.37315/sotocav20222905740\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Española de Cirugía Osteoarticular","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37315/sotocav20222905740","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Papel del biovidrio en el tratamiento de la osteomielitis focal crónica.
Bioactive glass emerges as an alternative to the classic two-stage treatment of chronic focal osteomyelitis. It allows the eradication of the infection in a single surgical act without the need to add a local antibiotic thanks to its mechanism of action, facilitating the filling of the residual bone defect after debridement. A retrospective review of 29 patients treated with bioactive glass was carried out in order to analyze the results and secondary complications. We observed a significant improvement in the analytical parameters, with complete remission of the infection in 80% of the patients. 31% showed wound serum leakage with spontaneous resolution in 55% of patients in the first 7 days after surgery. Therefore, bioactive glass is effective against multiple microorganisms, with good results in recurrence rate and few complications, even though long-term studies are required to confirm these results.