生物玻璃在慢性局灶性骨髓炎治疗中的作用。

ORTEGA YAGO, ARGÜELLES LINARES, BAEZA OLIETE
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引用次数: 1

摘要

生物活性玻璃作为慢性局灶性骨髓炎经典两阶段治疗的替代方案出现。由于其作用机制,可在一次手术中消除感染,而无需添加局部抗生素,有利于清创后残余骨缺损的填充。回顾性分析29例应用生物活性玻璃治疗的患者的治疗效果及继发并发症。我们观察到分析参数的显著改善,80%的患者感染完全缓解。31%的患者在术后7天内出现伤口血清渗漏,55%的患者自发消退。因此,生物活性玻璃对多种微生物有效,复发率好,并发症少,尽管需要长期研究来证实这些结果。
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Papel del biovidrio en el tratamiento de la osteomielitis focal crónica.
Bioactive glass emerges as an alternative to the classic two-stage treatment of chronic focal osteomyelitis. It allows the eradication of the infection in a single surgical act without the need to add a local antibiotic thanks to its mechanism of action, facilitating the filling of the residual bone defect after debridement. A retrospective review of 29 patients treated with bioactive glass was carried out in order to analyze the results and secondary complications. We observed a significant improvement in the analytical parameters, with complete remission of the infection in 80% of the patients. 31% showed wound serum leakage with spontaneous resolution in 55% of patients in the first 7 days after surgery. Therefore, bioactive glass is effective against multiple microorganisms, with good results in recurrence rate and few complications, even though long-term studies are required to confirm these results.
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