危重产科患者早期发现急性肾损伤的危险因素和结局

A. A. El-Hafez, A. Mahjoub, E. Ahmad
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引用次数: 2

摘要

背景:急性肾损伤(Acute kidney injury, AKI)是妊娠及产后重症监护室(ICU)护士面临的最具挑战性和最严重的并发症之一。有一个统一的识别和分类AKI的标准将提高重症护理护士识别这些患者的能力,并带来更好的结果。目的:探讨产科ICU重症产科患者早期发现急性肾损伤的危险因素及预后。设计。本研究采用描述性横断面研究设计。参与者:埃及Assiut市妇女保健医院产科ICU收治的338名妇女的总样本。方法:使用三种工具。工具1由研究人员开发,包括人口统计学和产科史、实验室参数、AKI引起的并发症和结果。顺序器官衰竭评估(SOFA)评分作为确定患者器官功能程度或衰竭率的工具II。根据急性肾损伤网络(AKIN)标准(工具III),测定血清肌酐和尿量用于早期识别AKI分期。结果:产科ICU住院的产科患者AKI患病率为10.1%;其中52.9%需要肾脏替代治疗,死亡率为29.4%。产后出血是AKI最常见的原因,发生率为41.2%。研究还发现,74.5%的AKI患者出现并发症。结论:在研究期间,AKI合并率为10.1%。与严重子痫前期、子痫、HEELP和急性脂肪肝APH等危险因素相比,产后出血是最常见的危险因素,SOFA评分非常显著。
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The risk factors and outcome of early identified acute kidney injury among critically ill obstetric patients
Background: Acute kidney injury (AKI) is one of the most challenging and serious complications of pregnancy and postpartum period that facing critical care nurses in Intensive Care Unit (ICU). Having a uniform standard for identifying and classifying AKI would enhance critical care nurses’ ability to recognize these patients and leading to better outcomes. Objective : This work aimed to explore the risk factors and outcome of early identified acute kidney injury of critically obstetric patients in Obstetric ICU. Design. A descriptive cross sectional research design was used in this study. Participants: A total sample of 338 women admitted to Obstetric ICU at Woman Health Hospital, Assiut City, Egypt. Method: Three tools were used.Tool I was developed by the researcher and included demographic and obstetric history, lab parameters, complications and outcomes arising from AKI. The Sequential Organ Failure Assessment (SOFA) score as tool II to determine the extent of a patient's organ function or rate of failure. Measurement of serum creatinine and urine output were used to early identify AKI stages according to Acute Kidney Injury Network (AKIN) Criteria (tool III). Results: The prevalence of AKI among obstetric patients admitted to obstetric ICU was 10.1%; of them 52.9% needed renal replacement therapy and the mortality rate was 29.4%. Postpartum hemorrhage was the most common cause of AKI and its prevalence was 41.2%. It was also found that 74.5% of AKI patients developed complications. Conclusion: AKI complicated 10.1% of total admitted women to the OICU in the studied period. Postpartum hemorrhage represents the most prevalent risk factors with a highly significant SOFA score compared to other risk factors as sever preeclampsia, eclampsia, HEELP & APH with acute fatty liver.
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