像素化硅正电子敏感成像探头

S. Huh, D. Burdette, E. Chesi, K. Honscheid, H. Kagan, C. Lacasta, G. Llosá, M. Mikuž, S. Park, W. Rogers, A. Studen, P. Weilhammer, N. Clinthorne
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引用次数: 2

摘要

一种像素化硅正电子敏感成像探针正在开发中,用于精确定位积聚18F-FDG的表面肿瘤。18F-FDG一直是一种令人感兴趣的放射性同位素,主要是因为它在肿瘤中的高吸收率和相对较短的正电子范围。硅探测器对高能光子的探测效率一般较低,可用于正电子的探测。我们提出了一种像素化硅正电子敏感成像探头,其像素尺寸为1.4 × 1.4 × 1.0 mm,等效电子噪声为~1.2 keV FWHM。小的像素尺寸带来了高的空间分辨率。探针运动结合适当的重建将允许亚像素分辨率的实现。此外,高能量分辨率使得从沉积的β能量谱中获得深度信息成为可能。我们讨论了蒙特卡罗模拟的数据,这将有助于预测完成器件的各种配置的性能。我们还报告了一个简单实验装置的初步数据
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A pixelated silicon positron sensitive imaging probe
A pixelated silicon positron sensitive imaging probe is under development to precisely localize superficially located tumors accumulating 18F-FDG. 18F-FDG has been a radioisotope of interest mainly because of the high uptake in tumors and the relatively short positron range. Silicon detectors have generally low detection efficiency for high energy photons and can be used for positron detection. We present a pixelated silicon positron sensitive imaging probe that has the 1.4-by-1.4-by-1.0 mm pixel size with equivalent electronic noise of ~1.2 keV FWHM. The small pixel size leads to the high spatial resolution. Probe movement in conjunction with appropriate reconstruction will allow sub-pixel resolution to be achieved. In addition the high energy resolution makes it possible to get depth information from the spectrum of deposited beta energies. We discuss data from Monte Carlo simulations, which will be useful for predicting performance of various configurations of completed devices. Also we report preliminary data from a simple experimental setup
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