类风湿性关节炎

N. K. Wardani, R. H. Masduchi
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摘要

类风湿性关节炎(RA)是一种慢性、全身性、炎症性疾病,主要影响周围小关节。在美国,类风湿性关节炎的年平均发病率为每1000人中每年0.5人。男女比例为3:1。该病可在20-60岁发病。类风湿性关节炎的确切病因尚不清楚。主要理论认为它是由环境因素、遗传易感性或免疫原性引起的。RA的诊断包括在最大改善前至少一小时出现晨僵,三个或更多关节关节炎,手部关节关节炎,对称关节炎,类风湿结节,血清类风湿因子阳性和x线片改变(手和手腕)。类风湿关节炎的定义是存在四个或更多的标准,标准1到4必须存在至少六周。一位44岁的女性从10年前开始手部疼痛和僵硬断断续续。她在洗澡等日常生活活动(ADL)和做饭、洗衣服等职业活动上都有困难。检查发现肘关节、手腕和手指活动范围受限,左中指和右小指胸孔孔畸形。x光检查发现手指关节有糜烂。给予的康复方案包括ROM运动、温和的伸展运动、手指夹板和ADL修改。我们建议她定期服用类风湿性药物(美洛昔康、甲基强的松、氯喹),锻炼,佩戴夹板,做好关节保护计划。治疗的目标是缓解疼痛,维持关节的活动范围和灵活性,通过关节运动调节进一步预防畸形,从而提高生活质量。
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Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic, systemic, inflammatory disorder that primarily affects small peripheral joints.  The average annual incidence of RA in the United States is 0.5 per 1000 persons per year. Female : male ratio of 3:1. Onset of the disease can occur at age ranging 20–60 years old. The precise cause of RA is unknown.Major theories mention it’s caused by environmental factors, genetic predisposition or immunogenic.Diagnosis of RA include morning stiffness at least one hour before maximal improvement, arthritis of three or more joints, arthritis of the hand joints, symmetric arthritis, rheumatoid nodules, positive serum rheumatoid factor and radiographic changes (hand and wrist). Rheumatoid arthritis is defined by the presence of four or more criteria and criteria 1 through 4 must be present for at least six weeks.A 44 year-old woman with pain and stiffness in her hand on and off since 10 years ago. She had difficulty doing her daily living activities (ADL) such as taking a bath and vocational activities such as cooking and washing clothes. On examination there were range of motion (ROM) limitation of the elbow, wrist and fingers, boutonnière deformity on left middle finger and right little finger. On X-ray examination we found erosion on finger joints.The rehabilitation program given were ROM exercises, gentle stretching exercises, finger splint and ADL modifications. We advised her to take the rheumatoid medication regularly (meloxicam, methylprednisolon and chloroquin), do exercises, wear the splint, and do the joint protection program. The goals of treatment were pain relief, maintenance of joint range of motion and mobility, further deformity prevent with joint motion modification therefore improving the quality of life.
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