H. de Jong, L. Perk, G. Visser, R. Boellaard, G. V. van Dongen, A. Lammertsma
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引用次数: 10
摘要
本研究利用三维高分辨率PET (high resolution research tomograph, HRRT)扫描仪确定了影响68Ga、124I和89zr定量精度的成像特性，并与18F进行了比较。虽然在这些同位素的灵敏度上发现了很大的差异，这可以用它们的正电子丰度来解释，但没有任何评估的成像特征阻止同位素用于(高分辨率)定量PET成像。但是，必须注意对死区时间、背景和散射以及部分体积使用精确的校正方法
High resolution PET imaging characteristics of /sup 68/Ga, /sup 124/I and /sup 89/Zr compared to /sup 18/F
In this study the imaging characteristics influencing the quantitative accuracy of 68Ga, 124I and 89 Zr were determined and compared to those of 18F using a 3D high resolution PET (high resolution research tomograph, HRRT) scanner. Although there were large discrepancies found in the sensitivity of these isotopes, which can be explained by their positron abundancy, none of the assessed imaging characteristic prevents the isotopes for usage in (high resolution) quantitative PET imaging. Care has to be taken, however, that accurate correction methods are used for dead time, background and scatter, and partial volume
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