健康人结合胆汁酸的肠肝循环:定量描述和功能。

Exposes annuels de biochimie medicale Pub Date : 1977-01-01

A F Hofmann

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引用次数: 0

摘要

一个多室模型描述了在稳态条件下的人结合胆汁酸的肠肝循环。该模型包含共轭;解偶联和再偶联;脱羟基;磺化、脱硫及产物;脱氢;还有立体选择性再氢化。动态描述肠肝循环和简要描述胆汁酸功能在健康和疾病功能障碍也进行了讨论。

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The enterohepatic circulation of conjugated bile acids in healthy man: quantitative description and functions.

A multicompartmental model describing the enterohepatic circulation of conjugated bile acids in man under steady-state conditions is proposed. The model encompasses conjugation; deconjugation and reconjugation; dehydroxylation; sulfation, desulfation and resulfation; dehydrogenation; and stereoselective rehydrogenation. A dynamic description of the enterohepatic circulation and a brief description of bile acid functions in health and dysfunctions in disease are also discussed.

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Exposes annuels de biochimie medicale

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