可生物降解医用聚合物的降解建模

Taohong Zhang, Liwei Li, Ruiwu Xin, Bingru Yang
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引用次数: 1

摘要

本文的目的是建立可生物降解医用高分子材料降解过程的数学模型。为了使生物可降解高分子材料能够成功地应用于医学领域,对其降解过程进行了研究。根据表面和内部化学反应机理不同的现象,建立了分区域、分时间的降解模型。对所建立的退化模型进行了求解。在本文中,我们将该模型应用于板的退化计算。通过对Pan模型的计算结果、实验值和计算值的比较,得出该模型比Pan模型更接近实验结果的结论,该模型具有实验合理性。
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Degradation Modeling of Biodegradable Medical polymer
The purpose of this article is to establish a mathematical model for the degradation process of biodegradable medical polymer materials. In order to making biodegradable polymer materials can be applied to the medical field successfully, an study about its degradation process is carried out. A sub-regional, sub-time degradation model is established according to the phenomenon that chemical reaction mechanism of surface and internal is not the same. The calculation is performed to solve the degradation model which we have established. In this article, we apply this model into the calculation of plate degradation. By the comparison of the calculation results, the experiment values and the calculated values of Pan's model, a conclusion that this model is closer to experimental results compared with Pan's model, and that this model is reasonable to experiment.
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