免疫层析条和显微镜在尼日利亚扎里亚选定儿童尿路血吸虫病诊断中的比较研究

Abdulraheem Hafeezah, E. Elijah
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摘要

由于卫生条件差和无法获得饮用水,血吸虫病在许多发展中国家仍然流行。本研究旨在确定尿路血吸虫病在选定儿童中的流行情况。从选定人群中随机抽取100份尿样,采用CCA快速免疫层析试纸和显微镜对血血吸虫卵进行筛选。最后观察到,在所检查的100个样本中,显微镜检查的患病率为8(8%),免疫层析试纸条检查的患病率为14(14%)。观察结果显示,儿童中血红梭菌感染的流行率相似;男童发病率最高。显微镜和免疫层析试纸条感染率以9 ~ 11岁年龄组最高,分别为23.8%和38.1%,男性感染率高于女性。48例男性患者镜检阳性5例(10.4%),试纸阳性10例(20.8%)。52例女性,镜检阳性3例(5.8%),试纸阳性4例(7.7%)。70%的家庭用水来自钻孔,20%来自水井,4%来自河流/溪流,6%来自其他来源。总共有10%的孩子经常在附近的水体游泳,6%的孩子钓鱼。在本次调查中,与血红梭菌相关的危险因素是饮用湖泊水、在湖泊或池塘中游泳以及这些湖泊中存在蜗牛(Bolinus)。有关地区应采取卫生控制措施,防止市民在露天排便。
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Comparative studies of immunochromatographic strips and microscopy in the diagnosis of urinary schistosomiasis in selected children in Zaria, Nigeria
Schistosomiasis remains endemic in many developing countries due to poor hygiene and access to potable water sources. The study was conducted to determine the prevalence of urinary schistosomiasis in selected children. A total of 100 urine samples were collected randomly from the selected population and screened using the CCA rapid immunochromatographic test strips and microscopy for the ova of the Schistosoma haematobium . It was observed at the end that out of the 100 samples examined, the prevalence was found to be 8(8%) for microscopy and 14(14%) for immunochromatographic test strips. The observation shows similar prevalence of S. haematobium infection in children; with the highest prevalence occurrences in male children. The age group 9-11 years had the highest prevalence rate of 23.8% and 38.1% for microscopy and immunochromatographic test strips respectively and males were more infected than females. Of 48 male subjects examined, 5(10.4%) were positive for microscopy while 10(20.8%) were positive for strips. Of 52 females, 3(5.8%) were positive for microscopy while 4(7.7%) were positive for strips. For 70%, their source of water for domestic purpose was bore hole, 20% was from the well, 4% from river/stream and 6% were from other sources. A total of 10% did swim regularly in nearby water bodies and 6% of the children go fishing.The risk factors associated with S. haematobium in this survey were drinking water from lakes, swimming in lakes or ponds and presence of snails ( Bolinus ) in such lakes. Sanitary control measures should be put in place in the areas so as to prevent people from defecating in the open.
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