石墨烯:生物医学用途的有前途的候选者

Eva Clithy
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引用次数: 1

摘要

石墨烯作为一种由sp2碳原子组成的新型二维纳米材料,具有独特的电学、光学和力学性能。目前,对石墨烯及其衍生物的研究主要集中在物理研究领域。石墨烯的化学和材料科学研究也在迅速发展,石墨烯在生物医学领域的研究工作才刚刚开始。氧化石墨烯是石墨烯的衍生物,具有较高的比表面积和丰富的官能团:底表面含有羟基和环氧基,边缘含有羧基。这些官能团赋予氧化石墨烯良好的亲水性、分散性和生物相容性,易于修饰和功能化,再加上其优异的光学性能,使氧化石墨烯在生物医学领域具有广阔的应用前景。本文简要介绍了石墨烯,特别是氧化石墨烯在生物和医学领域的最新进展,包括靶向药物递送、细胞成像、生物测定、肿瘤学和石墨烯生物安全性。
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Graphene: A Promising Candidate for Biomedical Use
As a new two-dimensional nanomaterial composed of sp2 carbon atom, graphene has unique electrical, optical and mechanical properties. At present, the research on graphene and its derivatives is mainly concentrated in the field of physics research. The chemical and material science research of graphene is also developing rapidly, and the research work of graphene in biomedicine field has just begun. Graphene oxide is a derivative of graphene, which has a high specific surface area and a rich functional group: the bottom surface contains a hydroxyl group and an epoxy group, and the edge contains a carboxyl group. These functional groups impart good hydrophilicity, dispersibility and biocompatibility to graphene oxide, are easy to modify and functionalize, and combined with their excellent optical properties, make graphene oxide have broad application prospects in the biomedical field. We herein briefly describe the recent advances in graphene, especially graphene oxide, in the biological and medical fields, including targeted drug delivery, cell imaging, bioassays, oncology, and graphene biosafety.
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