增强接触内窥镜-头颈部粘膜癌和癌前病变的新诊断方法

Peter Kántor, A. Švejdová, L. Staníková, K. Zeleník, P. Komínek
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摘要

头颈部粘膜病变的早期诊断是困难的。病变通常很小,恶性肿瘤有时看起来是良性的,反之亦然,而且患者的症状是非特异性的。这些问题可能导致恶性肿瘤诊断的延迟,或者相反,对肿瘤的组织学验证的不必要的快速指示。近年来,随着技术的进步,新的内镜方法(特别是窄带成像- NBI和IMAGE1 STM)改善了组织前诊断,可以更好地显示粘膜血管及其周围环境。另一种方法称为增强接触内窥镜(Enhanced Contact Endoscopy, ECE),它结合了放大光学和增强成像模式(如NBI和IMAGE1 S),能够准确评估被检查病变的粘膜血管。根据血管结构的变化,可以非常精确地评估病变的生物学特征。本文的目的是提供欧洲经委会的复杂概述。关键词内窥镜-喉镜-癌-活体显微镜-窄带成像-图像增强
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Enhanced contact endoscopy – new dia­gnostic method of cancerous and precancerous lesions of head and neck mucosa
Early dia­gnosis of mucosal lesions of the head and neck is difficult. The lesions are usually small, malignant tumours sometimes seem benign and vice versa, and the patients’ symptoms are nonspecific. These problems may lead to a delay in the dia­gnosis of malignant tumours, or on the contrary, to unnecessarily quick indication for histologic verification of the tumour. Technological advances in recent years improved the pre-histological dia­gnosis with new endoscopic methods (especially Narrow Band Imaging – NBI and IMAGE1 STM), which allowed a better visualization of the mucosal vessels and their surroundings. Another method, called Enhanced Contact Endoscopy (ECE), combines magnifying optics and enhanced imaging modes (such as NBI and IMAGE1 S) and enables accurate assessment of the mucosal vessels of the examined lesion. Based on the changes in the vascular architecture, it is possible to assess the bio­logical character of the lesion with great precision. The aim of this article is to provide a complex overview of ECE. Key words endoscopy – laryngoscopy – carcinoma – intravital microscopy – Narrow Band Imaging – image enhancement
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