{"title":"s9活化杂环胺的改进制备方法","authors":"S. Arimoto-Kobayashi, H. Hayatsu","doi":"10.3123/JEMS.25.77","DOIUrl":null,"url":null,"abstract":"We investigated improved methods for the preparation of metabolically activated forms of heterocyclic amines referred to as ‘activated heterocyclic amines’. We also described the influence of pH on the metabolic activation of Trp-P-2, and on the stability and mutagenicity of the activated form of Trp-P-2.","PeriodicalId":394432,"journal":{"name":"Environmental Mutagen Research","volume":"45 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2003-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Improved method for preparation of S9-activated heterocyclic amines\",\"authors\":\"S. Arimoto-Kobayashi, H. Hayatsu\",\"doi\":\"10.3123/JEMS.25.77\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We investigated improved methods for the preparation of metabolically activated forms of heterocyclic amines referred to as ‘activated heterocyclic amines’. We also described the influence of pH on the metabolic activation of Trp-P-2, and on the stability and mutagenicity of the activated form of Trp-P-2.\",\"PeriodicalId\":394432,\"journal\":{\"name\":\"Environmental Mutagen Research\",\"volume\":\"45 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2003-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Environmental Mutagen Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3123/JEMS.25.77\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental Mutagen Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3123/JEMS.25.77","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Improved method for preparation of S9-activated heterocyclic amines
We investigated improved methods for the preparation of metabolically activated forms of heterocyclic amines referred to as ‘activated heterocyclic amines’. We also described the influence of pH on the metabolic activation of Trp-P-2, and on the stability and mutagenicity of the activated form of Trp-P-2.
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