拉曼血液光谱及预测仪在子宫内膜异位症患者强化护理中的应用

E. Nsugbe
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摘要

子宫内膜异位症是一种流行的女性子宫内膜疾病,影响所有种族的妇女,在25-35岁年龄组中最常见。这种疾病没有明确的治疗方法,因此护理和管理是对付这种疾病的基本组成部分。目前,诊断该疾病的主要手段包括腹腔镜检查和不同的成像方式,而腹腔镜检查的仪器价格昂贵,需要临床专业知识。最近,一位作者利用拉曼血液光谱和机器学习实现了一种经济实惠的高通量方法来预测子宫内膜异位症。这项工作利用拉曼血液光谱数据集以及先进的信号处理、机器学习和临床控制论,设计了一种预测机器,该机器位于临床框架内,促进人机交互,以增强子宫内膜异位症患者的护理策略。预测机的设计初衷是预测患者是否患有该疾病,然后使用无监督学习来形成预测疾病程度的推理手段。结果表明,所采用的方法的组合可以允许子宫内膜异位症疾病的高预测。该领域的后续工作现在将包括进一步优化预测机,以潜在地最大化预测精度。
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On the use of Raman Blood Spectroscopy and Prediction Machines for Enhanced Care of Endometriosis Patients
Endometriosis is a prevalent disease of the female endometrium which affects women of all ethnicities and has been seen to be most common in the 25–35 years age group. The disease does not have a definitive cure, hence care and management are the essential components towards dealing with the disease. At present, the predominant means towards the diagnosis of the presence of the disease involves different imaging modalities alongside laparoscopy, where the instrumentation is expensive to acquire and requires clinical expertise. Recently, work has been done by an author who leveraged Raman blood spectroscopy alongside machine learning towards an affordable high throughput means towards the prediction of endometriosis.This work utilises the Raman blood spectroscopy dataset alongside advanced signal processing, machine learning and clinical cybernetics, towards the design of a prediction machine which sits within a clinical framework to facilitate Human-Machine interaction for an enhanced care strategy for patients with endometriosis. The prediction machine is designed to initially predict whether a patient has the disease, and is then followed by the use of unsupervised learning to form an inference means towards predicting the extent of the disease. The results showed that a combination of the adopted methods could allow for a high prediction of the endometriosis disease. Subsequent work in this area would now include further optimisation of the prediction machine in order to potentially maximise the prediction accuracy.
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