经颅刺激和阻抗成像的多电极系统

Tsepo Sadeq Montsi, A. Mishra
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引用次数: 1

摘要

最近的研究表明,通过对大脑进行无创低电流波形的应用,可以实现高度准确和有效的皮质刺激(经颅直流刺激)和成像(电阻抗断层扫描)系统。安全性和物理限制,以及个体独特的分形功能,大脑和周围颅组织的结构和电复杂性,阻碍了传统系统在神经治疗和研究中获得足够的精度和有效性。本文描述了一种能够同时实现增产和成像的新型系统,同时也改善了传统系统的缺点。这两种功能都需要分布在头皮上的多个独立控制的电极,并且具有互补的功能要求,因此需要最小的额外资源来实现这两个目标。满足这些需求还可以改进遗留模式。该系统超出了所有适当的安全要求,并采用模块化架构实现,支持硬件级联,从而可以根据应用程序的要求扩展系统功能和成本。虽然资源限制阻碍了满足关键的功能需求,但子系统的测试和模拟证明了进一步开发的概念是合理的。
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Multielectrode system for transcranial stimulation and impedance imaging
Recent works indicate that through the non-invasive application of low current waveforms to the brain, systems implementing both cortical stimulation (Transcranial Direct Current Stimulation) and imaging (Electrical Impedance Tomography) with a high degree of accuracy and effectiveness can be realised. Safety and physical constraints along with the individually unique and fractal-like functional, structural and electrical complexity of the brain and surrounding cranial tissue hinders legacy systems from achieving enough precision and effectiveness for neurological treatment and investigation. This paper describes a novel system capable of achieving both stimulation and imaging while also ameliorating the shortcomings of legacy systems. Both these functions require multiple independently controlled electrodes distributed on the scalp and have complimentary functional requirements, therefore minimal additional resources are required to achieve both goals. Meeting these requirements also result in the ability to improve on legacy modalities. The system exceeds all appropriate safety requirements and is implemented with a modular architecture enabling cascading of the hardware such that the system capability and cost can be scaled according to the requirements of the application. While resource constraints precluded meeting critical functional requirements, tests and simulation of the subsystems proved the concept justifying further development.
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