{"title":"低氧对辐射诱导大鼠肠道纤维化的保护作用。","authors":"J O Forsberg, H Jiborn, B Jung","doi":"10.3109/02841867909128191","DOIUrl":null,"url":null,"abstract":"<p><p>The protective effect of hypoxia, induced by degradable microspheres, against the development of fibrosis was investigated after single-dose irradiation of exteriorized rat ileum. Evaluation, based upon microscopy and analysis of hydroxyproline in protected and nonprotected gut segments, demonstrated an evident protective effect at doses of 15 to 25 Gy.</p>","PeriodicalId":75417,"journal":{"name":"Acta radiologica: oncology, radiation, physics, biology","volume":"18 1","pages":"65-75"},"PeriodicalIF":0.0000,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867909128191","citationCount":"18","resultStr":"{\"title\":\"Protective effect of hypoxia against radiation induced fibrosis in the rat gut.\",\"authors\":\"J O Forsberg, H Jiborn, B Jung\",\"doi\":\"10.3109/02841867909128191\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The protective effect of hypoxia, induced by degradable microspheres, against the development of fibrosis was investigated after single-dose irradiation of exteriorized rat ileum. Evaluation, based upon microscopy and analysis of hydroxyproline in protected and nonprotected gut segments, demonstrated an evident protective effect at doses of 15 to 25 Gy.</p>\",\"PeriodicalId\":75417,\"journal\":{\"name\":\"Acta radiologica: oncology, radiation, physics, biology\",\"volume\":\"18 1\",\"pages\":\"65-75\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1979-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3109/02841867909128191\",\"citationCount\":\"18\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta radiologica: oncology, radiation, physics, biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3109/02841867909128191\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta radiologica: oncology, radiation, physics, biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/02841867909128191","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Protective effect of hypoxia against radiation induced fibrosis in the rat gut.
The protective effect of hypoxia, induced by degradable microspheres, against the development of fibrosis was investigated after single-dose irradiation of exteriorized rat ileum. Evaluation, based upon microscopy and analysis of hydroxyproline in protected and nonprotected gut segments, demonstrated an evident protective effect at doses of 15 to 25 Gy.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
