C. Carraher, M. Roner, P. Slawek, Francesca Mosca, J. Frank, Lindsey C. Miller
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Groups 4 and 15 and Organotin Condensation Polymers for The Treatment of Cancers and Viruses
This short review describes the use of group 4 metallocenes, group 15 organometallics and organotin polymers in the treatment of human cancer tumors and viruses. These metal-containing polymers show good inhibition of all the main group solid tumors including pancreatic, lung, brain, breast, prostate and colon human cell lines. They also show inhibition of a variety of viruses including zika, herpes and vaccinia viruses. Synthesis of the polymers is rapid employing interfacial polymerization and commercially available reactants. They offer physicians a new class of drugs for the treatment of a variety of cancers and viruses.