利用互联网资源早期确认阿尔茨海默病

C. Sandeep, A. Sukesh Kumar
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引用次数: 1

摘要

阿尔茨海默病(AD)是痴呆症的一种常见形式,是一种不可逆的大脑神经退行性进行性疾病,影响65岁以上的老年人。阿尔茨海默病是一种脑部疾病,会导致记忆、思维和行为方面的问题。严重到足以干扰日常活动。阿尔茨海默病症状的特点是影响日常功能的记忆丧失、执行熟悉任务的困难、语言问题、时间和地点的迷失、判断能力差或下降、抽象思维问题、放错东西、情绪和行为改变、个性改变和丧失主动性。与阿尔茨海默病相关的检查有不同的类型,如神经心理测试、实验室测试和用于阿尔茨海默病早期诊断的各种成像方式。虽然这些测试是可用的,但它们不足以明确诊断该疾病。在本文中,我们重点介绍了与AD相关的数据库,如ADNI(阿尔茨海默病神经影像学倡议)、TREAD(轨迹相关的早期阿尔茨海默病数据库)、CAMD(主要疾病联盟)和NAAC(国家阿尔茨海默病协调中心)。利用这些互联网资源、软计算技术和不同成像方式的图像分析,有效地对AD进行明确诊断和早期确诊。我们的目标是在早期可靠地预测诊断,从而结合不同的测试值与软件计算技术的帮助下开发明确诊断的软件工具。
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The Early Confirmation of Alzheimer’s Disease using Internet Sources
Alzheimer Disease (AD) is one of the common forms of dementia which is an irreversible neurodegenerative progressive disorder of the brain which affects the elderly population above the age of 65. Alzheimer is a brain disease that causes problems with memory, thinking and behaviour. It is severe enough to interfere with daily activities. Alzheimer symptoms are characterized by memory loss that affects day-to-day function, difficulty performing familiar tasks, problems with language, disorientation of time and place, poor or decreased judgment, problems with abstract thinking, misplacing things, changes in mood and behaviour, changes in personality and loss of initiative. There are different types of tests associated with AD such as neuropsychological tests, laboratory tests and various imaging modalities for the early diagnosis of AD. Although these tests are available, they are inadequate for the definite diagnosis of the disease. In this paper we focus on the databases related to AD such as ADNI (Alzheimer’s Disease Neuroimaging Initiative), TREAD (Trajectory-Related Early Alzheimer’s Database), CAMD (Coalition Against Major Diseases), and NAAC( National Alzheimer’s Coordinating Center). The use of these internet sources, soft computing techniques and image analysis from the different imaging modalities in an efficient way for making a definite diagnosis and early confirmation of AD. Our aim is to predict the early diagnosis in a reliable manner such that to combine the values of different tests with the help of soft computing techniques to develop software tool for a definite diagnosis.
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