基因网络的群体智能导致生物细胞作为更高水平组织和器官发育的代理的行为规则

I. Tsigelny, V. Kouznetsova, S. Nigam
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引用次数: 0

摘要

我们提供了两个层次的描述器官发展为群体智能。器官发生过程是一个清晰的结构-功能系统,具有自组织(或SI组织)的性质。我们建议如何将其应用于肾脏发育的例子。我们讨论了基因和蛋白质如何被描述为SI代理。我们分析了导致下一级细胞组织-细胞相互作用的因子(基因,蛋白质等)的简化功能,并假设细胞作为下一级SI的因子的行为规则。我们还讨论了基因网络的必要特征,这些特征可能使细胞之间的“中继”信号传递成为可能。
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Swarm intelligence of gene networks leads to behavioral rules for biological cells to serve as agents for higher level tissue and organ development
We provide two-levels of description of organ development as swarm intelligences. The organogenesis process is a clear structure--function system with the property of self-organization (or SI organization). We suggest how this can be applied to the example of kidney development. We discuss how genes and proteins can be described as SI agents. We analyze simplified functions of agents (genes, proteins, etc.) that lead to organization of the next level of cell--cell interactions and postulate rules of behavior of the cells as agents of the next level SI. We also discuss the necessary features of the gene networks that may make it possible for "relay" signal transfer between the cells.
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