精神疾病的神经外科干预

C. Bervoets, B. Nuttin, L. Gabriëls
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引用次数: 0

摘要

精神疾病是世界上最普遍的疾病之一。药物治疗和心理治疗(单独或联合)都是治疗算法中的循证治疗步骤。在过去的几十年里,神经外科对精神疾病的干预已经引起了研究的兴趣,但很少被引入临床领域。然而,这些神经外科干预(即深部脑刺激(DBS)和病变神经外科)的疗效仍存在争议。我们对许多精神疾病的病理生理基础缺乏充分的了解。研究人员在一个精神适应症下研究多个神经解剖学靶点,并对一个脑靶点进行多重电刺激。增产参数的选择仍有待改进。
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Neurosurgical interventions for psychiatric disorders
Psychiatric disorders are among the most prevalent illnesses worldwide. Both medication and psychotherapy (alone or in combination) are evidence-based therapeutic steps in the treatment algorithm. In the past decades neurosurgical interventions for psychiatric disorders have attracted research interest and are sparsely introduced in the clinical field. The efficacy of these neurosurgical interventions (i.e. deep brain stimulation (DBS) and lesional neurosurgery) however remains under debate. We lack a full understanding of the pathophysiological basis of many psychiatric disorders. Researchers study multiple neuroanatomical targets within one psychiatric indication and multiple indications for electrical stimulation of one brain target. Stimulation parameter selection can still be improved.
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