脓毒症建模中的微分方程系统与无标度网络

R. Dobrescu, D. Andone, M. Dobrescu, S. Mocanu
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引用次数: 2

摘要

本文提出了一种模型之间的比较,缓解了脓毒症患者进化的特征,作为细胞水平的正确或错误的信息传递的结果。具体来说,比较了两种不同的细胞相互作用模型-一种基于三变量微分方程系统,另一种基于细胞相互作用无标度网络。最后讨论了每个模型在理解脓毒症现象中涉及的细胞信号网络结构方面的优点和局限性
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Differential Equations Systems versus Scale Free Networks in Sepsis Modeling
The paper proposes a comparison between models that relieves the characteristics of the patient evolution in sepsis as the result of correct or corrupted information transfer as the cell level. Specifically, two different models for the cellular interactions are compared - one based on a three variables system of differential equations, the other on a cellular interaction scale free network. The advantages and limits of each model in understanding the structure of cellular signaling networks involved in sepsis phenomena are finally discussed
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