宫颈癌合并异位肾的治疗及预后

M. Anand, Ankita Parikh, S. Shah
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摘要

盆腔恶性肿瘤同时发生异位肾是一种罕见的发现。以盆腔肾为表现的早期宫颈癌患者,首选手术治疗而非放疗,以避免对肾脏的照射。然而,在这种情况下,晚期宫颈癌的治疗面临困境,以调强放疗(IMRT)形式的适形放疗是首选。这有助于达到目标所需的剂量,同时减少对周围危险器官的剂量,特别是对盆腔肾的剂量。在此,我们报告一例国际妇产科联合会IIB期宫颈癌合并右盆腔肾异位的病例,患者为40岁女性,并成功地采用IMRT技术进行放化疗。随访2年,患者无疾病,肾功能正常。本文对文献中先前报道的盆腔恶性肿瘤伴异位肾的病例进行简要讨论。
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Carcinoma cervix with ectopic kidney, its treatment and outcome
The occurrence of pelvic malignancies along with an ectopic kidney is a rare finding. In the patients of early stage carcinoma of cervix presenting with pelvic kidney, surgery is preferred to radiation to avoid irradiating the kidney. However, advanced stage carcinoma of cervix in such scenario poses a therapeutic dilemma and conformal radiotherapy in the form of intensity-modulated radiotherapy (IMRT) is preferred option. This helps to achieve the desired dose to the target while reducing the dose to the surrounding organs at risk particularly to the pelvic kidney. Herein, we present a case of International Federation of Gynecology and Obstetrics Stage IIB carcinoma of cervix having ectopic right pelvic kidney in a 40-year-old female, and the patient was successfully treated with chemoradiotherapy in IMRT technique. The patient is disease free with normal renal function at 2-year follow-up. The previously reported cases of pelvic malignancies with ectopic kidney in the literature are discussed here briefly.
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