Is There A Ceiling Effect For Patient Controlled Analgesia Using Tramadol? A Case Report And Review Of The Literature.

Patient controlled analgesia (PCA) devices are a commonly used method of self-administered intravenous opioid titration postsurgery. Tramadol PCA has been shown to be a safe and effective modality of post-operative analgesia when compared with morphine. Reports of Tramadol toxicity are well documented in the literature; however there are no clear guidelines on maximal doses that should be administered by PCA. We report a case of seizure related to Tramadol and review the literature to determine a safe dosing range for Tramadol PCA.