单独和联合60Co辐射对小鼠B16黑色素瘤生长的影响。

A Wahl, T Brustad, J Mossige
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引用次数: 5

摘要

B16黑色素瘤生长在B6D2F1/BOM小鼠的尾部。描述了同时进行局部60Co辐照和热处理的程序。4 Gy剂量对肿瘤生长无影响;41.5℃热处理200 min效果不明显,而联合治疗可显著延缓肿瘤生长。大腿肿瘤在41.5℃下加热治疗2小时对肺转移的频率没有影响。
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Effect of hyperthermia alone and in combination with 60Co radiation on the growth of B16 melanoma in mice.

B16 melanoma was grown in the tail of B6D2F1/BOM mice. Procedures for simultaneous local 60Co irradiation and heat treatment are described. A dose of 4 Gy had no effect on tumour growth; heat treatment at 41.5 degrees C for 200 min had a minor effect, while the combined treatment caused a marked delay in tumor growth. Heat treatment of tumours in the thigh at 41.5 degrees C for 2 hours did not influence the frequency of lung metastases.

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