{"title":"单独和联合60Co辐射对小鼠B16黑色素瘤生长的影响。","authors":"A Wahl, T Brustad, J Mossige","doi":"10.3109/02841867909128221","DOIUrl":null,"url":null,"abstract":"<p><p>B16 melanoma was grown in the tail of B6D2F1/BOM mice. Procedures for simultaneous local 60Co irradiation and heat treatment are described. A dose of 4 Gy had no effect on tumour growth; heat treatment at 41.5 degrees C for 200 min had a minor effect, while the combined treatment caused a marked delay in tumor growth. Heat treatment of tumours in the thigh at 41.5 degrees C for 2 hours did not influence the frequency of lung metastases.</p>","PeriodicalId":75417,"journal":{"name":"Acta radiologica: oncology, radiation, physics, biology","volume":"18 4","pages":"343-56"},"PeriodicalIF":0.0000,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867909128221","citationCount":"5","resultStr":"{\"title\":\"Effect of hyperthermia alone and in combination with 60Co radiation on the growth of B16 melanoma in mice.\",\"authors\":\"A Wahl, T Brustad, J Mossige\",\"doi\":\"10.3109/02841867909128221\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>B16 melanoma was grown in the tail of B6D2F1/BOM mice. Procedures for simultaneous local 60Co irradiation and heat treatment are described. A dose of 4 Gy had no effect on tumour growth; heat treatment at 41.5 degrees C for 200 min had a minor effect, while the combined treatment caused a marked delay in tumor growth. Heat treatment of tumours in the thigh at 41.5 degrees C for 2 hours did not influence the frequency of lung metastases.</p>\",\"PeriodicalId\":75417,\"journal\":{\"name\":\"Acta radiologica: oncology, radiation, physics, biology\",\"volume\":\"18 4\",\"pages\":\"343-56\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1979-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3109/02841867909128221\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta radiologica: oncology, radiation, physics, biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3109/02841867909128221\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta radiologica: oncology, radiation, physics, biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/02841867909128221","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effect of hyperthermia alone and in combination with 60Co radiation on the growth of B16 melanoma in mice.
B16 melanoma was grown in the tail of B6D2F1/BOM mice. Procedures for simultaneous local 60Co irradiation and heat treatment are described. A dose of 4 Gy had no effect on tumour growth; heat treatment at 41.5 degrees C for 200 min had a minor effect, while the combined treatment caused a marked delay in tumor growth. Heat treatment of tumours in the thigh at 41.5 degrees C for 2 hours did not influence the frequency of lung metastases.