大面积肺栓塞的外科治疗。(报道了45例成功的栓塞手术,其中10例采用Trendelenburg技术)(作者译)。

R Kieny, B Eisenmann, B Jeanblanc, A Heitz, M Auad, M T Kieny, J Cinqualbre
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引用次数: 6

摘要

已有45例肺栓塞手术成功实施,其中10例采用Trendelenburg手术,35例采用体外循环。后一种方法取得了令人满意的结果(自1970年以来36次尝试中有34次存活),似乎是首选的方法。术中应避免任何肺部创伤;栓子切除术是通过血管内抽吸完成的。血流动力学状态始终异常:首发心脏骤停5例,重度休克20例(手术台上表现为心脏骤停9例),轻重度休克11例。9例患者的临床特征为发绀、呼吸窘迫和急性肺心病。9例患者在溶栓试验失败后行手术。30例患者术前均行肺血管造影,60 ~ 95%的患者均可见广泛的肺血管阻塞。这些数据对诊断和评估预后具有重要意义。尽管目前的药物治疗与纤维蛋白溶解,手术仍然是可取的治疗大面积肺栓塞。适应症是濒临死亡的病人,那些血栓溶解是禁忌或不成功的和那些有严重的肺阻塞(大于60%)。在后一个亚群中,溶栓治疗具有高死亡率。
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[Surgical treatment of massive pulmonary embolism. (Reported of 45 successful embolectomies inclusive 10 with Trendelenburg's technic) (author's transl)].

45 pulmonary embolectomies have been carried out successfully, 10 by Trendelenburg's procedure, 35 with extracorporeal circulation. The latter method gives satisfactory results (34 survivals out of 36 attempts since 1970) and appears to be the procedure of choice. Any pulmonary trauma should be avoided at operation; embolectomy is done by intra-vascular suction. The hemodynamic status was always abnormal: 5 initial cardiac arrests, 20 cases of severe shock (9 demonstrating cardiac arrest on the operating table) and 11 cases with less severe shock. In 9 cases cyanosis, respiratory distress and signs of acute cor pulmonale were the clinical features of the massive embolus. In 9 patients the operation was performed after an unsuccessful trial of thrombolysis. Preoperative pulmonary angiography could be performed in 30 cases and always showed extensive pulmonary vascular obstruction of 60 to 95 per cent. These data are important for diagnosis and for assessment of the prognosis. Despite of present medical treatment with fibrinolytics, surgery is still advisable in the treatment of massive pulmonary embolism. The indications are moribund patients, those in whom thrombolysis is contraindicated or unsuccessful and those with massive pulmonary obstruction (greater than 60 per cent). In this latter subset thrombolytic therapy carries a high level of mortality.

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