神经管缺损发生率与自然流产率的地域差异。

J Fedrick, P Adelstein
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引用次数: 9

摘要

为了证实Roberts和Lloyd(1973)的发现,即居住在南威尔士中枢神经系统畸形发生率相对较低的地区的妇女先前堕胎的发生率增加,我们检查了1958年英国围产期死亡率调查的数据。我们还发现有证据表明,本次调查中所有母亲的流产史在死产和无脑或脊柱裂导致的新生儿死亡率较低的地区略显普遍,但其数量级远低于威尔士研究。
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Area differences in the incidence of neural tube defect and the rate of spontaneous abortion.

In an attempt to corroborate the finding of Roberts and Lloyd (1973) of increased incidence of previous abortions in women living in those areas of South Wales with relatively low incidences of malformations of the central nervous system, we examined the data of the 1958 British Perinatal Mortality Survey. We also found evidence that the history of preceding abortion among all mothers in this survey was slightly more prevalent in areas where the rates of stillbirth and neonatal death from anencephalus or spina bifida were low, but the order of magnitude was much less than in the Welsh study.

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