A. Avanoğlu1, Ö. Herek1, I. Ulman1, O. Ergün1, A. Tünger2, M. Alkanat3, A. Erdener1
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Effects of H2 Receptor Blocking Agents on Bacterial Translocation in Burn Injury*
We experimentally studied the effects of Hz receptor block ers (ranitidine) on bacterial translocation (BT) in 42 male albino rals. Sham group (Group I, n .. 12 rau) wert' exposed to 21"C water while Bum group (Groop 11, n" lS rats) and Ranitidine group (Group 11I. n - 15 ratsl were exposed to 95" C hot water for 10 seconds to produce a full thidmess burn in 30 % of total body surface area. 300 mglkg ranitidine was administered to Group 11I starting immediately after the burn injury. Rats were sacrtficed on the fifth postbum day. Sham group gained weight while groups 11 and 11I had significant weight loss. Gastric pH increased with the admin-Resume
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