基于生物医学的癌症诊断决策自增强知识库

L. Sztandera
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引用次数: 2

摘要

提出了一种基于模糊集的知识库自动生成方法。作为概念验证,它最初被用于为纺织和服装公司制定监管/健康/环境指导规则。随后,该系统将得到扩展,以纳入更多的消费品,并在经过一些修改后,可以用作患者和临床医生个性化医疗中急需的卫生保健颠覆性工具。服装类别提供了一套不同的强制性法规和一些自愿标准。除AATCC对色牢度和甲醛的要求外,还考虑了CPSIA、FTC的护理和纺织品标签等强制性要求。最初的重点是致癌染料和色素。国际癌症研究机构(IARC)、美国国家毒理学计划(NTP)的数据库将与计算智能相结合,以识别工业过程或最终产品中存在的潜在毒素或致癌物,从而通过用户友好的界面提醒制造商和消费者。这种能力可以使用现代软件产品开发方法(包括设计思维、敏捷开发和Scrum)快速开发和验证,并将其推向市场,从而获得关键收益
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Self-augmenting Knowledge Base for Informed Decision Making With Biomedical Applications in Cancer Diagnosis
Fuzzy sets methodology to automatically generate knowledge base for informed decision making is proposed. As a proof of concept it has initially been applied to generate regulatory/health/environmental guidance rules for textile and apparel companies. Subsequently, the system will be augmented to incorporate additional consumer goods, and down the road, after some modifications, could be utilized as a much needed health care disruptor tool in personalized medicine for both patients and clinicians. The apparel category provides for a diverse set of mandatory regulations and some voluntary standards. Mandatory requirements such as CPSIA, FTC for Care and Textile labelling, in addition to AATCC requirements for colourfastness and formaldehyde were taken into consideration. Initial focus was on carcinogenic dyes and pigments. Databases from the International Agency for Research on Cancer (IARC), the US National Toxicology Program (NTP) are to be incorporated, in conjunction with computational intelligence, to identify potential toxins or carcinogens present in the industrial process or the final product, thus alerting manufactures and consumers through a user-friendly interface. This capability can be quickly developed and validated using modern software product development approaches incorporating Design Thinking, Agile Development with Scrum, and Business Model Generation to get this to market where key benefits can be derived
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