塔兰托工作人员玻璃体-视网膜疾病与大气颗粒物相关性研究

C. Giannico, F. Perri, A. Suppi, B. Trevisani, G. Oliva, O. Giannico, D. Clemente, M. Manigrasso, C. Vernale, P. Avino
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引用次数: 0

摘要

导言:一些流行病学研究已经强调了大气细颗粒物在死亡率、住院率和心血管系统呼吸系统疾病增加方面对健康的影响。本研究的目的是评估在塔兰托ILVA钢铁厂工作场所吸入空气中缺失的细颗粒物与玻璃体视网膜道疾病爆发的可能相关性。材料和方法:从2013年6月到2014年12月,对57名年龄在25至58岁之间在塔兰托ILVA钢铁厂工作的男性和52名年龄在25至58岁之间的塔兰托市居民进行了调查。每个患者都进行了全面的眼科检查,特别是对眼睛的后段进行了检查(使用Schepens装置的间接眼科检查)。所有受试者的视力完全正常,无视神经损伤。所有的一般和眼部病史显示没有值得注意的既往病史。然后对用卡方检验得到的数据进行统计分析,根据Yates进行校正,该校正适用于观测数小于500的情况。考虑的显著性水平为5%。因此,认为p <0.05具有统计学意义。结果:在工作过程中,两组间的差异有统计学意义。接受检查的工人中有84%患有视网膜疾病;在塔兰托市接受检查的居民中,有27%的人患有视网膜疾病。讨论:从所得数据可以假设,微呼吸细支气管阻塞可导致阻塞和随之而来的视网膜静脉充血。
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Investigation on the correlations between vitreo-retinal disorders and atmospheric particulate matter in individuals working in Taranto
Introduction: several epidemiological studies have already highlighted the effects that fine atmospheric particulate matter has on health in terms of increasing mortality, hospital admissions and also respiratory diseases in the cardiovascular system. The purpose of this study is to assess the possible correlation between inhalation of fine fraction of particulate matter missing in the air and disease outbreaks in vitreoretinal tract in the workplace of ILVA steel plant in Taranto. Materials and methods: from June 2013 to December 2014 were examined both 57 male individuals aged between 25 and 58 years, working at the ILVA steel plant in Taranto and 52 male individuals aged between 25 and 58 who were just residents in the city of Taranto. For each of them a complete eye examination was performed with particular reference to the posterior segment of the eye (indirect ophthalmoscopy with Schepens unit). All the examined individuals had visual acuity perfectly normal and no optic nerve lesion. All the general and ocular medical history revealed no pre-existing conditions worthy of note. It was then conducted a statistical analysis of the data obtained by means of a chi-squared test by applying the correction according to Yates, which is appropriately used when the number of observations is less than 500. The significance level considered was 5%. Therefore, they were considered statistically significant values of p <0.05. Results: during this work, statistical significance were highlighted between the two groups examined. The workers examined in 84% of cases have retinal disorders; 27% individuals had retinal disorders among residents examined in the city of Taranto. Discussion: from the resulting data can be assumed that micro-respiratory bronchiole blockages can lead to gridlock and consequent retinal venous congestion.
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