{"title":"声学显微镜下细胞-底物附着的观察","authors":"J. Hildebrand","doi":"10.1109/T-SU.1985.31600","DOIUrl":null,"url":null,"abstract":"Abstmcf-The scanning reflection acoustic microscope operating at 1.7 GHz is used to observe the contacts between living cells and their substrates. When the acoustic microscope lens is focused on the surface of the substrate, sites of cell-substrate attachment appear as darkened areas in the acoustic image. Quantitative analysis indicates that attachment sites have increased acoustic impedance relative to other regions within the cell. Acoustic images of moving cells show spatial and temporal changes in the impedance at the attachment site.","PeriodicalId":371797,"journal":{"name":"IEEE Transactions on Sonics and Ultrasonics","volume":"13 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1985-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"20","resultStr":"{\"title\":\"Observation of Cell-Substrate Attachment with the Acoustic Microscope\",\"authors\":\"J. Hildebrand\",\"doi\":\"10.1109/T-SU.1985.31600\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstmcf-The scanning reflection acoustic microscope operating at 1.7 GHz is used to observe the contacts between living cells and their substrates. When the acoustic microscope lens is focused on the surface of the substrate, sites of cell-substrate attachment appear as darkened areas in the acoustic image. Quantitative analysis indicates that attachment sites have increased acoustic impedance relative to other regions within the cell. Acoustic images of moving cells show spatial and temporal changes in the impedance at the attachment site.\",\"PeriodicalId\":371797,\"journal\":{\"name\":\"IEEE Transactions on Sonics and Ultrasonics\",\"volume\":\"13 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1985-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"20\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IEEE Transactions on Sonics and Ultrasonics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/T-SU.1985.31600\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Transactions on Sonics and Ultrasonics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/T-SU.1985.31600","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Observation of Cell-Substrate Attachment with the Acoustic Microscope
Abstmcf-The scanning reflection acoustic microscope operating at 1.7 GHz is used to observe the contacts between living cells and their substrates. When the acoustic microscope lens is focused on the surface of the substrate, sites of cell-substrate attachment appear as darkened areas in the acoustic image. Quantitative analysis indicates that attachment sites have increased acoustic impedance relative to other regions within the cell. Acoustic images of moving cells show spatial and temporal changes in the impedance at the attachment site.