Multi-task firework algorithm for cell tracking and contour estimation

Dynamics analysis of cells' lifecycle progression is essential in medical research. Multiple cells tracking through fluorescence microscopy imaging is often challenged by many roadblocks including the severe image noise and clutter, the occlusion and adhesion among cells, and the low resolution and contrast of image. To gain full dynamics of multiple cells, a novel multi-task firework explosion based tracking algorithm is proposed for multiple cells tracking in low contract image sequences in this paper. A conventional firework algorithm is used to determine the cell location, and a simplified firework explosion searching strategy is then adopted to estimate the cell contour. Simulation results verify the effectiveness of the methods.