TBI动物特征提取的自动八臂迷宫轨迹跟踪系统

Shu-Cing Wu, Chi-Yuan Lin, Liang-Jyun Hong, Chi-Chun Chen
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引用次数: 0

摘要

创伤性脑损伤(TBI)是现代社会最常见的意外伤害。认知和记忆衰退是脑外伤引起的常见现象。大多数基础实验用大鼠进行病理研究。此外,八臂迷宫常被用来测试脑疾病的空间学习行为,如阿尔茨海默病和创伤性脑损伤。然而,大多数迷宫实验数据都是手工记录的。这个过程需要大量的人力和时间。为此,本研究搭建了八臂迷宫自动跟踪轨迹系统,采集实验数据。此外,还可以及时记录大鼠的运动轨迹。最后,利用这些路径轨迹数据分析脑外伤动物的行为特征。结果表明,脑外伤大鼠有40%~80%的机会出现向右运动轨迹。
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Automated Eight-Arm Maze Trajectory Tracking System for Feature Extraction of TBI Animals
Traumatic Brain Injury (TBI) is most commonly accident injury in modern society. The deterioration of cognition and memory is a common phenomenon caused by TBI. Most of the basic experiments used rats for pathological research. Moreover, an eight-arm maze was often used to test the spatial learning behavior of brain diseases, such as Alzheimer’s disease and TBI. However, most of maze experimental data were collected in manual records. This process would take a lot of manpower and time. Therefore, the research built an automatic tracking trajectory system of the eight-arm maze to collect experiment data. Furthermore, the path trajectory of the rat can be recorded in time. Finally, these path trajectory data were used to analysis behavior feature of TBI animals. The results showed that TBI rats have a 40%~80% chance of having a trajectory to the right.
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