st段抬高型心肌梗死、多支冠状动脉病变及低射血分数患者行冠状动脉搭桥手术1例

Jalilov A.K.
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摘要

几十年来,冠状动脉旁路移植术(CABG)一直是冠状动脉疾病(包括急性冠状动脉综合征(ACS))患者心肌血运重建的主要方法。近几十年来,随着血管内介入技术的发展和药物洗脱支架的发展,经皮冠状动脉介入治疗(PCI)已成为ACS后血管重建术的主要方法。(1,6)。急性冠脉综合征(Acute coronary syndrome, ACS)包括不稳定型心绞痛(NS)、急性非st段抬高型心肌梗死(STEMI)、st段抬高型心肌梗死(STEMI)等临床表现。大约40%被诊断为ACS的患者有多支冠状动脉疾病,冠状动脉旁路移植术(CABG)比PCI更好。[2]. 大多数比较PCI和CABG的研究主要是针对稳定的冠状动脉疾病患者进行有计划的心肌血运重建,而不是那些需要急诊或紧急心肌血运重建的患者。因此,这些研究结果对ACS患者的适用性有限。然而,在确定ACS的最佳治疗方案时,这些研究的长期结果,特别是低再血运重建需求,较低的再心肌梗死率,以及CABG的生存益处,仍然需要考虑。目前对大多数ACS患者的治疗建议优先采用PCI或CABG进行早期血运重建[3,4]。因此,我们的主要目标是提供当前冠状动脉手术血运重建术的适应症和选择,包括当前的指南和最新发表的文献。在STEMI患者中,早期主要病变PCI仍然是金标准,因为它能提供最快的缺血心肌血运重建,并且通常比急诊CABG耐受性更好[5]。由于高达50%的STEMI患者患有多支冠状动脉疾病,建议在无心肌梗死的情况下进行早期动脉血运重建术,为心肌抢救、减少缺血分水岭和改善左心室功能提供最佳机会[6,7]。st段抬高型心肌梗死伴多支冠状动脉病变低射血分数患者搏动冠状动脉搭桥术成功一例。术后第11天出院,无并发症。
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CASE OF AORTOCORONARY BYPASS SURGERY IN A PATIENT WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION, MULTIVESSEL CORONARY LESIONS AND LOW EJECTION FRACTION
For decades, coronary artery bypass grafting (CABG) has been the main method of myocardial revascularization in patients with coronary artery disease, including those with acute coronary syndrome (ACS). Over the past decades, with the development of endovascular interventions and the development of drug-eluting stents, percutaneous coronary intervention (PCI) has become the main method of revascularization after ACS. [1,6]. Acute coronary syndrome (ACS) includes clinical manifestations such as unstable angina pectoris (NS), acute non-ST-segment elevation myocardial infarction (STEMI), and ST-segment elevation myocardial infarction (STEMI). Approximately 40% of all patients diagnosed with ACS have multivessel coronary artery disease, for which coronary artery bypass grafting (CABG) is better than PCI. [2]. The majority of studies comparing PCI and CABG have mainly included patients with stable coronary artery disease who underwent planned myocardial revascularization, rather than those requiring emergency or urgent myocardial revascularization. Thus, the results of these studies have limited applicability to patients with ACS. However, the long-term results of these studies, in particular the low need for re-revascularization, a lower rate of re-myocardial infarction, and the survival benefits of CABG, still need to be considered when determining the best course of treatment for ACS. The current recommendations for treatment in most patients with ACS give preference to early revascularization using PCI or CABG [3, 4]. Thus, our main goal here is to provide the current indications and options for surgical revascularization of the coronary arteries, including current guidelines and the latest published literature. In STEMI patients, early PCI of the main lesion remains the gold standard because it provides the fastest revascularization of the ischemic myocardium and is generally better tolerated than emergency CABG [5]. Since up to 50% of STEMI patients have multivessel coronary artery disease, early arterial revascularization without myocardial infarction has been recommended to provide optimal opportunities for myocardial rescue, reduction of ischemic watershed and improvement of left ventricular function [6,7]. A clinical case of successful beating coronary artery bypass grafting in a patient with ST-segment elevation myocardial infarction, multivessel coronary artery disease and low ejection fraction. The patient was discharged on the 11th day after surgery without complications.
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