原发性甲状腺瘤:一罕见病例报告

Megha Tandon
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摘要

原发性甲状腺淋巴瘤非常罕见。定义为累及甲状腺或腺体及局部淋巴结,诊断时无其他部位转移的淋巴瘤[1]。原发性甲状腺受累非常罕见,通常发生在淋巴细胞性甲状腺炎背景下的免疫异常腺体[2]。恶性淋巴瘤占所有甲状腺恶性肿瘤的1%-3.5%[3]。结外边缘区b细胞淋巴瘤粘膜相关淋巴组织(MALT型)常见于胃肠道黏膜。它们可能出现在唾液腺、肺、皮肤和其他部位,包括甲状腺。由于甲状腺的肿瘤过程和反应过程并存,使用细胞学和组织学诊断可能存在困难。需要免疫组织化学(IHC)和流式细胞术技术来确认maltoma的诊断[2]。
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Primary Thyroid Maltoma: A Rare Case Report
Primary thyroid lymphoma is very rare. It is defined as lymphoma involving the thyroid gland or the gland and regional lymph nodes with no metastasis of other areas at the time of diagnosis [1]. Primary involvement of thyroid is very rare, and it usually arises in immunologically abnormal gland in background of lymphocytic thyroiditis [2]. Malignant lymphoma constitutes 1%-3.5% of all the thyroid malignancies [3]. Extra nodal marginal zone B-cell lymphoma mucosa associated lymphoid tissue (MALT Type) usually occurs in mucosa of gastrointestinal tract. They may arise in salivary glands, lungs, skin and another site including thyroid. Because of the coexistence of neoplastic and reactive processes in thyroid, there may be difficulty in diagnosing maltoma using cytology and histology. Immunohistochemistry (IHC) and flowcytometry techniques are required to confirm the diagnosis of maltoma [2].
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