难治性重症肌无力:学得越多,知道得越少。

Ali A. Habib
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引用次数: 0

摘要

难治性重症肌无力指的是尽管使用了多种免疫调节疗法,但症状控制不足、持续肌肉无力和疲劳的患者。这篇文章强调了目前对难治性重症肌无力的了解,并强调了主要的知识空白,提请注意我们对这一疾病子集的理解中未满足的需求。这篇综述提出了一些问题,关于我们目前对难治性疾病的理解,以及新出现的数据和治疗方法如何改变我们的思维和患者的病程。
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Refractory myasthenia gravis: the more we learn, the less we know.
Refractory myasthenia gravis identifies the group of patients that have inadequate symptom control and persistent muscle weakness and fatigability despite the use of multiple immune modulatory therapies. This manuscript highlights what is currently known about refractory myasthenia gravis and underlines major knowledge gaps, drawing attention to the unmet needs in our understanding of this disease subset. This review raises questions about our current understanding of refractory disease and how emerging data as well as therapies may alter our thinking and patients’ disease course.
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