小型动物螺旋SPECT扫描仪

Mingshan Sun, E. Izaguirre, T. Funk, A. Hwang, J. Carver, S. Thompson, B. Patt, K. Parnham, T. Vandehei, Junqiang Li, B. Hasegawa
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引用次数: 4

摘要

小动物成像依赖于锥形束重建几何图形来实现高空间分辨率的微spect和微ct。然而,正常的圆轨道锥束几何结构提供了一个有限的视场,这对于微spect来说具有不均匀的灵敏度和空间分辨率。这些限制可以通过使用更复杂的探测器来解决,比如螺旋轨道。在本文中,我们提出了一个小动物螺旋SPECT系统,该系统使用CZT探测器来获取具有良好能量分辨率和空间分辨率的放射性核素数据。它包括一个集成滑环的龙门,用于连续的检测器旋转和一个自动的动物床平移。仿真研究和实验数据表明,该扫描仪提高了轴向空间分辨率,延长了轴向视场
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A small animal helical SPECT scanner
Small animal imaging relies on cone-beam reconstruction geometries to achieve high spatial resolution for both microSPECT and microCT. However, normal circular-orbit cone-beam geometries offer a restricted field of view which for microSPECT has nonuniform sensitivity and spatial resolution. These limitations can be addressed by using a more complex detector orbit such a helix. In this paper, we present a small animal helical SPECT system which uses CZT detectors to acquire radionuclide data with excellent energy resolution and spatial resolution. It incorporates a gantry with integrated slip-ring for continuous detector rotation and an automated animal bed for translation. Both simulation studies and experimental data show this scanner improves the axial spatial resolution and lengthens the field of view in the axial direction
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