缺血性心肌病100例临床、心电图及超声心动图分析。

Mainul Islam, M. A. Ali, U. H. Ferdaushi, S. Nabi, Sayeedur Rahman Khan, Shariful Islam, H. Mahmoud
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引用次数: 0

摘要

背景:缺血性心脏病(IHD)是全球发病率和死亡率的主要原因之一。缺血性心肌病(ICM)是IHD的一种迟发性并发症,表现为扩张性心肌病伴心室功能下降,不能完全归因于冠状动脉阻塞或缺血性损伤。目的:探讨缺血性心肌病患者的临床、心电图和超声心动图特征。方法:对2015年3月至2015年9月在达卡NICVD住院或门诊就诊的100例缺血性心肌病患者进行横断面观察研究。在满足纳入和排除标准后进行患者入组。收集临床、心电图、超声心动图资料并进行数据分析。结果:100例患者资料分析,年龄40 ~ 80岁,平均年龄61.4±7.9岁。79%的受试者为男性。最常见的症状是呼吸困难(93%)、胸痛(73%)、心悸(39%)和水肿(23%)。大多数患者为NYHA功能级lV(43%)。64%有前路心肌梗死史,22%有下路心肌梗死,25%有H/O PTCA, 7%有冠脉搭桥。71%的受试者有心动过速,65%的受试者有肺基底音,56%的受试者收缩压低于100 MMHG, 25%的受试者有水肿。心电图表现如下:窦性心律85%,窦性心动过速71%,房颤15%,LBBB 34%, RBBB 12%,前表面病理Q 65%,下表面病理Q 21%,非特异性ST-T改变41%,室性早搏17%。超声心动图显示52%的患者出现前壁运动障碍,43%的患者出现全身运动障碍。平均左室射血分数(LVEF) 31±5.9%,平均左室舒张内径(LVIDd) 6.5±0.4 cm。(59%)受试者二尖瓣返流(MR)为一级,20%为二级。结论:缺血性心肌病的临床表现因人而异。症状的严重程度与左心室收缩功能障碍的严重程度、左心室直径和二尖瓣返流等级相关。前路心肌梗死更容易发展为缺血性心肌病。孟加拉国心脏杂志2020;35(2): 121-127
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Clinical, Electrocardiographic and Echocardiographic Profile of Ischemic Cardiomyopathy: An analysis of 100 cases.
Background: Ischemic heart disease (IHD) is one of the leading cause of morbidity and mortality worldwide. Ischemic cardiomyopathy (ICM) is a delayed complication of IHD that arises as dilated cardiomyopathy with depressed ventricular function, which cannot be attributed entirely to coronary artery obstruction or ischemic injury. Objectives: To evaluate the clinical, electrocardiographic and echocardiographic profile of patients presenting with ischemic cardiomyopathy. Methods: In this cross sectional observational study 100 patients of ischemic cardiomyopathy admitted in hospital or visited OPD in NICVD, Dhaka from March’15 to Sept’15 were studied. Enrollment of the patients were done after fulfilling the inclusion and exclusion criteria. Clinical, electrocardiographic and echocardiographic data were collected then data analysis was done. Results: Data analysis of 100 patients was showed age range was 40-80 years and mean age was 61.4±7.9 years. 79% subjects were male. Most common symptoms were dyspnea (93%), chest pain(73%), palpitation (39%) and edema (23%). Most patients were in NYHA functional class lV (43%). 64% cases had history of anterior myocardial infarction (MI), 22% had inferior MI, 25% had H/O PTCA and 7% had CABG. 71% subjects had tachycardia, 65% had lungs basal rales, 56% had systolic blood pressure below 100 mmhg and 25% had edema. ECG findings was as follows sinus rhythm (85%), Sinus tachycardia 71%, AF 15%, LBBB 34%, RBBB 12%, pathological Q in anterior surface 65% and inferior surface 21%, non specific ST-T changes 41% and PVCs was found in 17%.On echocardiography ,anterior wall hypokinesia was seen in 52% and global hypokinesia in 43%. Mean left ventricular ejection fraction (LVEF) was 31±5.9% and mean left ventricular internal diastolic diameter (LVIDd) was 6.5±0.4 cm. (59%) subjects had mitral regurgitation (MR) grade-l and 20% had MR grade-ll. Conclusion: The clinical presentation of ischemic cardiomyopathy varies from patient to patient. Severity of symptoms correlates with severity of left ventricular systolic dysfunction, left ventricular diameter and mitral regurgitation grade . Anterior Myocardial infarction has more chance to develop ischemic cardiomyopathy. Bangladesh Heart Journal 2020; 35(2) : 121-127
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