Mechtilde Schäfer, Matthias Walz, R. Stein, Lars Vollmer, Günther Schuster, A. Foitzik
{"title":"用于dna分析的goepingen发生器","authors":"Mechtilde Schäfer, Matthias Walz, R. Stein, Lars Vollmer, Günther Schuster, A. Foitzik","doi":"10.1142/S1465876303001848","DOIUrl":null,"url":null,"abstract":"So far the verification of specific bacteria is time consuming and costly. The reason is the neccessity for highly specialised laboratory equipment and the requirements regarding clean-room facilities ensuring environments free of any germs. Additionally growing bacteria in equivalent petri dishes may require quite some time until a reasonable number is grown sufficient for further evaluation. For many bacteria and even viruses alternative processes for multiplication have been developed, basically relying on the so called Polymerase Chain Reaction (PCR). We developed the Goeppingen GeneReactor, a microsized system (MEMS) for PCR as a low cost device, that can be used without any clean-room facilities, while additionally a device for electrophoresis is added as a tool for analysis. Thus this system can be used as a throw analysis tool, i.e. specimen containig the required bacteria or viruses could be preparated and investigated in every physician's pratice. It should be noted, that even tiny amounts of st...","PeriodicalId":331001,"journal":{"name":"Int. J. Comput. Eng. Sci.","volume":"6 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2003-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Goeppingen Genereactor For Dna-Analysis\",\"authors\":\"Mechtilde Schäfer, Matthias Walz, R. Stein, Lars Vollmer, Günther Schuster, A. Foitzik\",\"doi\":\"10.1142/S1465876303001848\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"So far the verification of specific bacteria is time consuming and costly. The reason is the neccessity for highly specialised laboratory equipment and the requirements regarding clean-room facilities ensuring environments free of any germs. Additionally growing bacteria in equivalent petri dishes may require quite some time until a reasonable number is grown sufficient for further evaluation. For many bacteria and even viruses alternative processes for multiplication have been developed, basically relying on the so called Polymerase Chain Reaction (PCR). We developed the Goeppingen GeneReactor, a microsized system (MEMS) for PCR as a low cost device, that can be used without any clean-room facilities, while additionally a device for electrophoresis is added as a tool for analysis. Thus this system can be used as a throw analysis tool, i.e. specimen containig the required bacteria or viruses could be preparated and investigated in every physician's pratice. It should be noted, that even tiny amounts of st...\",\"PeriodicalId\":331001,\"journal\":{\"name\":\"Int. J. Comput. Eng. Sci.\",\"volume\":\"6 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2003-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Int. J. Comput. Eng. Sci.\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1142/S1465876303001848\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Int. J. Comput. Eng. Sci.","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1142/S1465876303001848","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
So far the verification of specific bacteria is time consuming and costly. The reason is the neccessity for highly specialised laboratory equipment and the requirements regarding clean-room facilities ensuring environments free of any germs. Additionally growing bacteria in equivalent petri dishes may require quite some time until a reasonable number is grown sufficient for further evaluation. For many bacteria and even viruses alternative processes for multiplication have been developed, basically relying on the so called Polymerase Chain Reaction (PCR). We developed the Goeppingen GeneReactor, a microsized system (MEMS) for PCR as a low cost device, that can be used without any clean-room facilities, while additionally a device for electrophoresis is added as a tool for analysis. Thus this system can be used as a throw analysis tool, i.e. specimen containig the required bacteria or viruses could be preparated and investigated in every physician's pratice. It should be noted, that even tiny amounts of st...