磷酸奥司他韦(达菲®)被认为是诱因的急性出血性肠炎的1例

諭 米田, 洋三 小林, 剛洋 布居, 幸祐 竹田, 篤史 松森, 稔 安藤, 裕久 辻之上, 公男 西村, 博志 福井
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引用次数: 6

摘要

例一名23岁妇女因下腹疼痛、腹泻和便血入院,诊断为乙型流感。她的家庭医生在前一天开始使用神经氨酸酶抑制剂(奥司他韦)治疗。结肠镜检查显示左侧横结肠出血和糜烂。停止奥司他韦治疗后,这些症状消失,结肠镜检查结果有所改善。药物诱导淋巴细胞刺激试验奥司他韦阳性。这是首例报道的奥司他韦引起的急性出血性结肠炎。
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リン酸オセルタミビル(タミフル®)が誘因と考えられた急性出血性腸炎の1例
: A 23-year-old woman had lower abdominal pain, diarrhea and bloody stool was admitted and given a diagnosis of influenza B. Her home doctor had started treatment by neuraminidase inhibitor (oseltamivir) the previous day. Colonoscopic examination revealed an area of hemorrhage and erosion in the left transverse colon. After halting oseltamivir treatment these symptoms disappeared and her colonoscopic findings improved. A drug-induced lymphocyte stimulation test was positive for oseltamivir. This case is the first reported case of acute hemorrhagic colitis induced by oseltamivir.
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